Yondelis and Intestinal obstruction - a phase IV clinical study of FDA data

Summary:

Intestinal obstruction is reported as a side effect among people who take Yondelis (trabectedin), especially for people who are female, 50-59 old, have been taking the drug for < 1 month also take Doxorubicin Hydrochloride, and have Ovarian cancer.

The phase IV clinical study analyzes which people have Intestinal obstruction when taking Yondelis. It is created by eHealthMe based on reports of 1,220 people who have side effects when taking Yondelis from the FDA, and is updated regularly.

What is Yondelis?

Yondelis has active ingredients of trabectedin. eHealthMe is studying from 1,220 Yondelis users. Check the latest studies of Yondelis.

What is Intestinal obstruction?

Intestinal obstruction is found to be associated with 1,886 drugs and 2,613 conditions by eHealthMe. Check the latest studies of Intestinal obstruction.

On Jul, 19, 2026

1,220 people reported to have side effects when taking Yondelis.
Among them, 15 people (1.23%) have Intestinal obstruction.

Could Yondelis cause Intestinal obstruction?

Among these 15 people:

How long have people been on Yondelis when they have Intestinal obstruction? *

What is the gender of people who have Intestinal obstruction when taking Yondelis? *

female: 100 %
male: 0.0 %

What is the age of people who have Intestinal obstruction when taking Yondelis? *

What are other drugs people take besides Yondelis? *

Doxorubicin Hydrochloride: 3 people, 20.00%
Innohep: 2 people, 13.33%
Paclitaxel: 1 person, 6.67%
Novalgin: 1 person, 6.67%
Levothyroxine Sodium: 1 person, 6.67%
Carboplatin: 1 person, 6.67%
Avastin: 1 person, 6.67%

What are other side effects people have besides Intestinal obstruction? *

Pleural Effusion (water on the lungs): 2 people, 13.33%
Infected Lymphocele (infected abnormal collection of lymphatic fluid): 2 people, 13.33%
Bicytopenia (two parameters from the full blood count are low, the term bicytopenia can be used): 2 people, 13.33%
Acute Kidney Failure: 2 people, 13.33%
Stress And Anxiety: 1 person, 6.67%
Ovarian Cancer (cancer of ovary): 1 person, 6.67%
Neoplasm Malignant (cancer tumour): 1 person, 6.67%
High Blood Pressure: 1 person, 6.67%
Hepatic Failure (liver failure): 1 person, 6.67%
Dyspnea (difficult or laboured breathing): 1 person, 6.67%

What are the existing conditions these people have? *

Ovarian Cancer Recurrent (reoccurrence of ovary cancer): 6 people, 40.00%
Ovarian Cancer (cancer of ovary): 6 people, 40.00%
Pain: 2 people, 13.33%
High Blood Pressure: 2 people, 13.33%
Embolism (obstruction of an artery, typically by a clot of blood or an air bubble): 2 people, 13.33%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Yondelis and have Intestinal obstruction?

- Check whether Intestinal obstruction is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Yondelis:

Yondelis (1,220 reports)

Browse all side effects of Yondelis:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Intestinal obstruction:

Intestinal obstruction (1,886 drugs)

Browse all the conditions that are associated with Intestinal obstruction:

Intestinal obstruction (2,613 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on trabectedin (the active ingredients of Yondelis) and Yondelis (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.