Zafirlukast and Hoarseness or changing voice - a phase IV clinical study of FDA data

Summary:

Hoarseness or changing voice is reported as a side effect among people who take Zafirlukast (zafirlukast), especially for people who are female, 60+ old, have been taking the drug for 6 - 12 months also take Omeprazole, and have Chronic obstructive pulmonary disease.

The phase IV clinical study analyzes which people have Hoarseness or changing voice when taking Zafirlukast. It is created by eHealthMe based on reports of 1,076 people who have side effects when taking Zafirlukast from the FDA, and is updated regularly.

What is Zafirlukast?

Zafirlukast has active ingredients of zafirlukast. It is often used in asthma. eHealthMe is studying from 1,091 Zafirlukast users. Check the latest studies of Zafirlukast.

What is Hoarseness or changing voice?

Hoarseness or changing voice is found to be associated with 1,777 drugs and 2,666 conditions by eHealthMe. Check the latest studies of Hoarseness or changing voice.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

1,076 people reported to have side effects when taking Zafirlukast.
Among them, 25 people (2.32%) have Hoarseness or changing voice.

Could Zafirlukast cause Hoarseness or changing voice?

Among these 25 people:

How long have people been on Zafirlukast when they have Hoarseness or changing voice? *

What is the gender of people who have Hoarseness or changing voice when taking Zafirlukast? *

female: 56 %
male: 44 %

What is the age of people who have Hoarseness or changing voice when taking Zafirlukast? *

What are other drugs people take besides Zafirlukast? *

Omeprazole: 12 people, 48.00%
Flovent: 10 people, 40.00%
Tylenol W/ Codeine No. 3: 10 people, 40.00%
Combivent: 9 people, 36.00%
Warfarin Sodium: 8 people, 32.00%
Proair Hfa: 4 people, 16.00%
Accolate: 3 people, 12.00%
Simvastatin: 3 people, 12.00%
Spiriva: 3 people, 12.00%
Vitamin D3: 3 people, 12.00%

What are other side effects people have besides Hoarseness or changing voice? *

Nausea (feeling of having an urge to vomit): 11 people, 44.00%
Throat Irritation: 11 people, 44.00%
Renal Cell Carcinoma Stage Unspecified (kidney cancer in unknown stage): 10 people, 40.00%
Dry Throat: 9 people, 36.00%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 24.00%
Laryngeal Oedema (swelling of larynx): 5 people, 20.00%
Aphonia (inability to produce voice): 5 people, 20.00%
Feeling Abnormal: 4 people, 16.00%
Tremor (trembling or shaking movements in one or more parts of your body): 4 people, 16.00%
Dry Skin: 4 people, 16.00%

What are the existing conditions these people have? *

Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 3 people, 12.00%
Mycotic Allergy (fungal allergy): 2 people, 8.00%
Multiple Myeloma (cancer of the plasma cells): 2 people, 8.00%
Colon Cancer: 2 people, 8.00%
Type 2 Diabetes: 1 person, 4.00%
Tardive Dyskinesia (a disorder that involves involuntary movements): 1 person, 4.00%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 4.00%
Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 1 person, 4.00%

* Approximation only. Some reports may have incomplete information.

Do you take Zafirlukast and have Hoarseness or changing voice?

- Check whether Hoarseness or changing voice is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Zafirlukast:

Zafirlukast (1,091 reports)

Browse all side effects of Zafirlukast:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hoarseness or changing voice:

Hoarseness or changing voice (1,777 drugs)

Browse all the conditions that are associated with Hoarseness or changing voice:

Hoarseness or changing voice (2,666 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on zafirlukast (the active ingredients of Zafirlukast) and Zafirlukast (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.