Zantac and Peritonitis - a phase IV clinical study of FDA data

Summary:

Peritonitis is reported as a side effect among people who take Zantac (ranitidine hydrochloride), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Lasix, and have Pain.

The phase IV clinical study analyzes which people have Peritonitis when taking Zantac. It is created by eHealthMe based on reports of 432,014 people who have side effects when taking Zantac from the FDA, and is updated regularly.

What is Zantac?

Zantac has active ingredients of ranitidine hydrochloride. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 434,161 Zantac users. Check the latest studies of Zantac.

What is Peritonitis?

Peritonitis (inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen and covers most of the abdominal organs) is found to be associated with 1,050 drugs and 1,576 conditions by eHealthMe. Check the latest studies of Peritonitis.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 27, 2026

432,014 people reported to have side effects when taking Zantac.
Among them, 77 people (0.02%) have Peritonitis.

Among these 77 people:

How long have people been on Zantac when they have Peritonitis? *

What is the gender of people who have Peritonitis when taking Zantac? *

female: 48.05 %
male: 51.95 %

What is the age of people who have Peritonitis when taking Zantac? *

What are other drugs people take besides Zantac? *

What are other side effects people have besides Peritonitis? *

Hypotension (abnormally low blood pressure): 13 people, 16.88%
Sepsis (a severe blood infection that can lead to organ failure and death): 13 people, 16.88%
Fever: 10 people, 12.99%
Pneumonia: 9 people, 11.69%
Respiratory Acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease): 8 people, 10.39%
Dizziness: 8 people, 10.39%
Nausea (feeling of having an urge to vomit): 8 people, 10.39%
Constipation: 7 people, 9.09%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 7 people, 9.09%
Diverticular Perforation (serious gastrointestinal condition in which the intestine's walls are perforated): 7 people, 9.09%

What are the existing conditions these people have? *

Pain: 8 people, 10.39%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 5 people, 6.49%
High Blood Pressure: 3 people, 3.90%
Muscle Spasms (muscle contraction): 3 people, 3.90%
Constipation: 3 people, 3.90%
Pancreatic Carcinoma Stage Ii (pancreatic cancer stage ii): 3 people, 3.90%
Stress And Anxiety: 3 people, 3.90%
High Blood Cholesterol: 3 people, 3.90%
Gastric Disorder (disease of stomach): 2 people, 2.60%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 2 people, 2.60%

* Approximation only. Some reports may have incomplete information.

Do you take Zantac and have Peritonitis?

- Check whether Peritonitis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Zantac:

Zantac (434,161 reports)

Peritonitis treatments and more:

Peritonitis (27,277 reports)

Browse all side effects of Zantac:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Peritonitis:

Peritonitis (1,050 drugs)

Browse all the conditions that are associated with Peritonitis:

Peritonitis (1,576 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on ranitidine hydrochloride (the active ingredients of Zantac) and Zantac (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.