Zarontin and Memory loss - a phase IV clinical study of FDA data

Summary:

Memory loss is reported as a side effect among people who take Zarontin (ethosuximide), especially for people who are male, 60+ old, have been taking the drug for 2 - 5 years also take Keppra, and have Seizures.

The phase IV clinical study analyzes which people have Memory loss when taking Zarontin. It is created by eHealthMe based on reports of 958 people who have side effects when taking Zarontin from the FDA, and is updated regularly.

What is Zarontin?

Zarontin has active ingredients of ethosuximide. It is often used in petit mal seizure. eHealthMe is studying from 987 Zarontin users. Check the latest studies of Zarontin.

What is Memory loss?

Memory loss is found to be associated with 2,726 drugs and 4,378 conditions by eHealthMe. Check the latest studies of Memory loss.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Sep, 03, 2026

958 people reported to have side effects when taking Zarontin.
Among them, 21 people (2.19%) have Memory loss.

Could Zarontin cause Memory loss?

Among these 21 people:

How long have people been on Zarontin when they have Memory loss? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 50 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 50 %

What is the gender of people who have Memory loss when taking Zarontin? *

  • female: 38.89 %
  • male: 61.11 %

What is the age of people who have Memory loss when taking Zarontin? *

  • 0-1: 0.0 %
  • 2-9: 11.11 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 11.11 %
  • 40-49: 16.67 %
  • 50-59: 27.78 %
  • 60+: 33.33 %

What are other drugs people take besides Zarontin? *

  1. Keppra: 9 people, 42.86%
  2. Dilantin: 6 people, 28.57%
  3. Valium: 6 people, 28.57%
  4. Lamictal: 5 people, 23.81%
  5. Lipitor: 5 people, 23.81%
  6. Neurontin: 5 people, 23.81%
  7. Tegretol: 5 people, 23.81%
  8. Zyrtec: 4 people, 19.05%
  9. Protonix: 4 people, 19.05%
  10. Coenzyme Q10: 4 people, 19.05%

What are other side effects people have besides Memory loss? *

  1. Speech Impairment (Adult) (inability to speak (adult)): 6 people, 28.57%
  2. Balance Disorder: 6 people, 28.57%
  3. Impaired Driving Ability: 5 people, 23.81%
  4. Weakness: 5 people, 23.81%
  5. Cerebral Small Vessel Ischaemic Disease (inadequate blood supply to small blood vessel of brain): 4 people, 19.05%
  6. Compression Fracture (fracture due to pressure caused by injury): 4 people, 19.05%
  7. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 4 people, 19.05%
  8. Lumbar Vertebral Fracture: 4 people, 19.05%
  9. Coordination Abnormal (abnormal movement): 4 people, 19.05%
  10. Acute Cerebellar Ataxia (disorder of the nervous system-sudden onset of a disturbance in coordination): 4 people, 19.05%

What are the existing conditions these people have? *

  1. Seizures (abnormal excessive or synchronous neuronal activity in the brain): 9 people, 42.86%
  2. High Blood Pressure: 5 people, 23.81%
  3. High Blood Cholesterol: 5 people, 23.81%
  4. Cardiac Disorder: 4 people, 19.05%
  5. Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 4 people, 19.05%
  6. Cough: 4 people, 19.05%
  7. Depression: 4 people, 19.05%
  8. Gastric Disorder (disease of stomach): 4 people, 19.05%
  9. Wheezing (a high-pitched whistling sound made while you breath): 4 people, 19.05%
  10. Pain: 4 people, 19.05%

* Approximation only. Some reports may have incomplete information.

Do you take Zarontin and have Memory loss?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Zarontin:

Memory loss treatments and more:

How severe was Memory loss and when was it recovered:

Expand to all the drugs that have ingredients of ethosuximide:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Zarontin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Memory loss:

Browse all the conditions that are associated with Memory loss:


How the study uses the data?

The study uses data from the FDA. It is based on ethosuximide (the active ingredients of Zarontin) and Zarontin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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