Zegerid and Weight loss - a phase IV clinical study of FDA data

Summary:

Weight loss is reported as a side effect among people who take Zegerid (omeprazole; sodium bicarbonate), especially for people who are female, 30-39 old, have been taking the drug for 10+ years also take Protonix, and have Pain.

The phase IV clinical study analyzes which people have Weight loss when taking Zegerid. It is created by eHealthMe based on reports of 2,985 people who have side effects when taking Zegerid from the FDA, and is updated regularly.

What is Zegerid?

Zegerid has active ingredients of omeprazole; sodium bicarbonate. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 3,220 Zegerid users. Check the latest studies of Zegerid.

What is Weight loss?

Weight loss is found to be associated with 1,444 drugs and 2,297 conditions by eHealthMe. Check the latest studies of Weight loss.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Jul, 20, 2026

2,985 people reported to have side effects when taking Zegerid.
Among them, 30 people (1.01%) have Weight loss.

Among these 30 people:

How long have people been on Zegerid when they have Weight loss? *

What is the gender of people who have Weight loss when taking Zegerid? *

female: 73.33 %
male: 26.67 %

What is the age of people who have Weight loss when taking Zegerid? *

What are other drugs people take besides Zegerid? *

What are other side effects people have besides Weight loss? *

Hypokalemia (low potassium): 20 people, 66.67%
Constipation: 19 people, 63.33%
Stress And Anxiety: 18 people, 60.00%
Abdominal Distension: 15 people, 50.00%
Dyspnea (difficult or laboured breathing): 15 people, 50.00%
Abdominal Pain: 14 people, 46.67%
Left Ventricular Hypertrophy (the thickening of the myocardium (muscle) of the left ventricle of the heart): 14 people, 46.67%
Back Pain: 14 people, 46.67%
Oedema Peripheral (superficial swelling): 13 people, 43.33%
Nausea (feeling of having an urge to vomit): 13 people, 43.33%

What are the existing conditions these people have? *

Pain: 11 people, 36.67%
Hypersensitivity: 6 people, 20.00%
Blood Pressure Abnormal: 4 people, 13.33%
Diarrhea: 4 people, 13.33%
Stress And Anxiety: 3 people, 10.00%
Inflammatory Bowel Disease: 3 people, 10.00%
Gastric Ph Decreased: 3 people, 10.00%
Renal Disorder (kidney disease): 3 people, 10.00%
Depression: 3 people, 10.00%
Incontinence (lack of moderation or self-control): 3 people, 10.00%

* Approximation only. Some reports may have incomplete information.

Do you take Zegerid and have Weight loss?

- Check whether Weight loss is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Zegerid:

Zegerid (3,220 reports)

Weight loss treatments and more:

Weight loss (62,432 reports)

How severe was Weight loss and when was it recovered:

Weight loss in Zegerid

Expand to all the drugs that have ingredients of omeprazole; sodium bicarbonate:

Weight loss and drugs with ingredients of omeprazole; sodium bicarbonate (31 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Zegerid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Weight loss:

Weight loss (1,444 drugs)

Browse all the conditions that are associated with Weight loss:

Weight loss (2,297 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on omeprazole; sodium bicarbonate (the active ingredients of Zegerid) and Zegerid (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.