Zenpep and Stroke - a phase IV clinical study of FDA data

Summary:

Stroke is reported as a side effect among people who take Zenpep (pancrelipase (amylase;lipase;protease)), especially for people who are male, 60+ old, have been taking the drug for 6 - 12 months also take Ondansetron, and have Cystic fibrosis.

The phase IV clinical study analyzes which people have Stroke when taking Zenpep. It is created by eHealthMe based on reports of 5,490 people who have side effects when taking Zenpep from the FDA, and is updated regularly.

What is Zenpep?

Zenpep has active ingredients of pancrelipase (amylase;lipase;protease). eHealthMe is studying from 5,529 Zenpep users. Check the latest studies of Zenpep.

What is Stroke?

Stroke (sudden death of a portion of the brain cells due to a lack of oxygen) is found to be associated with 2,340 drugs and 3,028 conditions by eHealthMe. Check the latest studies of Stroke.



On Jun, 15, 2026

5,490 people reported to have side effects when taking Zenpep.
Among them, 23 people (0.42%) have Stroke.

Could Zenpep cause Stroke?

Among these 23 people:

How long have people been on Zenpep when they have Stroke? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 100 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Stroke when taking Zenpep? *

  • female: 23.08 %
  • male: 76.92 %

What is the age of people who have Stroke when taking Zenpep? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 11.11 %
  • 20-29: 0.0 %
  • 30-39: 11.11 %
  • 40-49: 0.0 %
  • 50-59: 22.22 %
  • 60+: 55.56 %

What are other drugs people take besides Zenpep? *

  1. Flomax: 5 people, 21.74%
  2. Ondansetron: 5 people, 21.74%
  3. Oxycodone: 4 people, 17.39%
  4. Xarelto: 3 people, 13.04%
  5. Percocet: 3 people, 13.04%
  6. Grape Seed Extract: 3 people, 13.04%
  7. Lidocaine And Prilocaine: 3 people, 13.04%
  8. Lovenox: 3 people, 13.04%
  9. Marinol: 3 people, 13.04%
  10. Metformin: 3 people, 13.04%

What are other side effects people have besides Stroke? *

  1. Acute Coronary Syndrome (acute chest pain and other symptoms that happen because the heart does not get blood): 2 people, 8.70%
  2. Cerebral Artery Embolism (sudden blocking of an artery by a clot or foreign material): 2 people, 8.70%
  3. Embolism (obstruction of an artery, typically by a clot of blood or an air bubble): 2 people, 8.70%
  4. Diplopia (double vision): 2 people, 8.70%
  5. Vith Nerve Paralysis: 2 people, 8.70%
  6. Hypoaesthesia (reduced sense of touch or sensation): 2 people, 8.70%
  7. Hypotension (abnormally low blood pressure): 2 people, 8.70%
  8. Iiird Nerve Disorder: 2 people, 8.70%
  9. Death: 2 people, 8.70%
  10. Myocarditis (inflammation of heart muscle myocardium): 2 people, 8.70%

What are the existing conditions these people have? *

  1. Cystic Fibrosis (disease of the secretary glands): 4 people, 17.39%
  2. Nausea (feeling of having an urge to vomit): 3 people, 13.04%
  3. Diabetes: 3 people, 13.04%
  4. Adenocarcinoma Pancreas (cancer of pancreas): 2 people, 8.70%
  5. Pseudomonas Infection (pseudomonas infection is caused by a bacterium, pseudomonas aeruginosa): 2 people, 8.70%
  6. Pancreatic Carcinoma Metastatic (pancreatic cancer- metastatic): 2 people, 8.70%
  7. Pain: 2 people, 8.70%
  8. Joint Pain: 2 people, 8.70%
  9. Back Pain: 1 person, 4.35%
  10. Blood Pressure Abnormal: 1 person, 4.35%

* Approximation only. Some reports may have incomplete information.

Do you take Zenpep and have Stroke?

- Check whether Stroke is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Zenpep:

Stroke treatments and more:

How severe was Stroke and when was it recovered:

Expand to all the drugs that have ingredients of pancrelipase (amylase;lipase;protease):

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Zenpep:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Stroke:

Browse all the conditions that are associated with Stroke:


How the study uses the data?

The study uses data from the FDA. It is based on pancrelipase (amylase;lipase;protease) (the active ingredients of Zenpep) and Zenpep (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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