Zepatier and Indigestion - a phase IV clinical study of FDA data

Summary:

Indigestion is reported as a side effect among people who take Zepatier (elbasvir; grazoprevir), especially for people who are female, 50-59 old, have been taking the drug for 1 - 6 months also take Cosentyx, and have Hepatitis c.

The phase IV clinical study analyzes which people have Indigestion when taking Zepatier. It is created by eHealthMe based on reports of 4,481 people who have side effects when taking Zepatier from the FDA, and is updated regularly.

What is Zepatier?

Zepatier has active ingredients of elbasvir; grazoprevir. eHealthMe is studying from 4,482 Zepatier users. Check the latest studies of Zepatier.

What is Indigestion?

Indigestion is found to be associated with 2,413 drugs and 3,419 conditions by eHealthMe. Check the latest studies of Indigestion.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 04, 2026

4,481 people reported to have side effects when taking Zepatier.
Among them, 56 people (1.25%) have Indigestion.

Among these 56 people:

How long have people been on Zepatier when they have Indigestion? *

What is the gender of people who have Indigestion when taking Zepatier? *

female: 60.87 %
male: 39.13 %

What is the age of people who have Indigestion when taking Zepatier? *

What are other drugs people take besides Zepatier? *

Acetaminophen: 15 people, 26.79%
Calcium Carbonate: 15 people, 26.79%
Ramipril: 15 people, 26.79%
Celebrex: 15 people, 26.79%
Cetirizine Hydrochloride: 15 people, 26.79%
Prednisone: 15 people, 26.79%
Phenylephrine Hydrochloride: 15 people, 26.79%
Fish Oil: 15 people, 26.79%
Oxycodone Hydrochloride: 15 people, 26.79%
Cosentyx: 15 people, 26.79%

What are other side effects people have besides Indigestion? *

Nausea (feeling of having an urge to vomit): 18 people, 32.14%
Insomnia (sleeplessness): 16 people, 28.57%
Pemphigus (any of several acute or chronic skin diseases characterized by groups of itching blisters): 15 people, 26.79%
Fever: 15 people, 26.79%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 15 people, 26.79%
Pneumonia: 15 people, 26.79%
Pericarditis (inflammation of the pericardium): 15 people, 26.79%
Pain In Extremity: 15 people, 26.79%
Oedema (fluid collection in tissue): 15 people, 26.79%
Mobility Decreased (ability to move is reduced): 15 people, 26.79%

What are the existing conditions these people have? *

Hepatitis C: 25 people, 44.64%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 15 people, 26.79%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 14 people, 25.00%
Psoriasis (immune-mediated disease that affects the skin): 14 people, 25.00%
Stress And Anxiety: 2 people, 3.57%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 2 people, 3.57%
Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 1 person, 1.79%
Secondary Hypertension (elevated blood pressure that results from an underlying, identifiable, often correctable cause): 1 person, 1.79%
Hepatitis (inflammation of the liver): 1 person, 1.79%
Hepatic Cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue): 1 person, 1.79%

* Approximation only. Some reports may have incomplete information.

Do you take Zepatier and have Indigestion?

- Check whether Indigestion is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Zepatier:

Zepatier (4,482 reports)

Indigestion treatments and more:

Indigestion (445,031 reports)

Browse all side effects of Zepatier:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Indigestion:

Indigestion (2,413 drugs)

Browse all the conditions that are associated with Indigestion:

Indigestion (3,419 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on elbasvir; grazoprevir (the active ingredients of Zepatier) and Zepatier (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.