Zeposia and Constipation - a phase IV clinical study of FDA data

Summary:

Constipation is reported as a side effect among people who take Zeposia (ozanimod hydrochloride), especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months also take Mirena, and have Ulcerative colitis.

The phase IV clinical study analyzes which people have Constipation when taking Zeposia. It is created by eHealthMe based on reports of 6,371 people who have side effects when taking Zeposia from the FDA, and is updated regularly.

What is Zeposia?

Zeposia has active ingredients of ozanimod hydrochloride. eHealthMe is studying from 6,372 Zeposia users. Check the latest studies of Zeposia.

What is Constipation?

Constipation is found to be associated with 3,004 drugs and 4,613 conditions by eHealthMe. Check the latest studies of Constipation.



On Jul, 24, 2026

6,371 people reported to have side effects when taking Zeposia.
Among them, 54 people (0.85%) have Constipation.

Could Zeposia cause Constipation?

Among these 54 people:

How long have people been on Zeposia when they have Constipation? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 100 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Constipation when taking Zeposia? *

  • female: 84.91 %
  • male: 15.09 %

What is the age of people who have Constipation when taking Zeposia? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 10.42 %
  • 30-39: 12.5 %
  • 40-49: 18.75 %
  • 50-59: 22.92 %
  • 60+: 35.42 %

What are other drugs people take besides Zeposia? *

  1. Vitamin D3: 2 people, 3.70%
  2. Vitamin B12: 2 people, 3.70%
  3. Omega 3: 2 people, 3.70%
  4. Mirena: 2 people, 3.70%
  5. Vyvanse: 1 person, 1.85%
  6. Tysabri: 1 person, 1.85%
  7. Promethazine: 1 person, 1.85%
  8. Probiotic: 1 person, 1.85%
  9. Ondansetron: 1 person, 1.85%
  10. Miralax: 1 person, 1.85%

What are other side effects people have besides Constipation? *

  1. Diarrhea: 11 people, 20.37%
  2. Fatigue (feeling of tiredness): 11 people, 20.37%
  3. Headache (pain in head): 8 people, 14.81%
  4. Nausea (feeling of having an urge to vomit): 6 people, 11.11%
  5. Haematochezia (passage of stools containing blood): 5 people, 9.26%
  6. Abdominal Distension: 5 people, 9.26%
  7. Abdominal Pain Upper: 5 people, 9.26%
  8. Oropharyngeal Pain: 4 people, 7.41%
  9. Flatulence (flatus expelled through the anus): 4 people, 7.41%
  10. Haemorrhage (bleeding): 4 people, 7.41%

What are the existing conditions these people have? *

  1. Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 25 people, 46.30%
  2. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 21 people, 38.89%
  3. Fungal Infection: 2 people, 3.70%
  4. Breast Cancer: 2 people, 3.70%
  5. Nausea (feeling of having an urge to vomit): 1 person, 1.85%
  6. Irritable Bowel Syndrome: 1 person, 1.85%
  7. Heart Palpitations (feelings or sensations that your heart is pounding or racing): 1 person, 1.85%
  8. Depression: 1 person, 1.85%
  9. Abdominal Pain: 1 person, 1.85%

* Approximation only. Some reports may have incomplete information.

Do you take Zeposia and have Constipation?

- Check whether Constipation is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Zeposia:

Constipation treatments and more:

How severe was Constipation and when was it recovered:

Expand to all the drugs that have ingredients of ozanimod hydrochloride:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Zeposia:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Constipation:

Browse all the conditions that are associated with Constipation:


How the study uses the data?

The study uses data from the FDA. It is based on ozanimod hydrochloride (the active ingredients of Zeposia) and Zeposia (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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