Zinacef and Stroke - a phase IV clinical study of FDA data

Summary:

Stroke is reported as a side effect among people who take Zinacef (cefuroxime sodium), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Trasylol, and have High blood pressure.

The phase IV clinical study analyzes which people have Stroke when taking Zinacef. It is created by eHealthMe based on reports of 1,789 people who have side effects when taking Zinacef from the FDA, and is updated regularly.

What is Zinacef?

Zinacef has active ingredients of cefuroxime sodium. eHealthMe is studying from 1,802 Zinacef users. Check the latest studies of Zinacef.

What is Stroke?

Stroke (sudden death of a portion of the brain cells due to a lack of oxygen) is found to be associated with 2,376 drugs and 3,011 conditions by eHealthMe. Check the latest studies of Stroke.

On Dec, 27, 2025

1,789 people reported to have side effects when taking Zinacef.
Among them, 37 people (2.07%) have Stroke.

Among these 37 people:

How long have people been on Zinacef when they have Stroke? *

What is the gender of people who have Stroke when taking Zinacef? *

female: 32.43 %
male: 67.57 %

What is the age of people who have Stroke when taking Zinacef? *

What are other drugs people take besides Zinacef? *

What are other side effects people have besides Stroke? *

Stress And Anxiety: 35 people, 94.59%
Injury: 33 people, 89.19%
Pain: 32 people, 86.49%
Acute Kidney Failure: 32 people, 86.49%
Fear: 29 people, 78.38%
Anhedonia (inability to experience pleasure from activities usually found enjoyable): 23 people, 62.16%
Renal Injury (kidney injury): 23 people, 62.16%
Emotional Distress: 23 people, 62.16%
Renal Impairment (severely reduced kidney function): 21 people, 56.76%
Depression: 17 people, 45.95%

What are the existing conditions these people have? *

High Blood Pressure: 6 people, 16.22%
Bleeding Disorders: 4 people, 10.81%
Diabetes: 2 people, 5.41%
Alcohol Withdrawal Syndrome: 2 people, 5.41%
Post Procedural Haemorrhage (post procedural bleeding): 2 people, 5.41%
Arrhythmias (irregular heartbeat): 2 people, 5.41%
Hypovolaemic Shock (shock caused by severe blood or fluid loss): 2 people, 5.41%
Back Pain: 2 people, 5.41%
Headache (pain in head): 2 people, 5.41%
Urine Output - Decreased: 2 people, 5.41%

* Approximation only. Some reports may have incomplete information.

Do you take Zinacef and have Stroke?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Zinacef:

Zinacef (1,802 reports)

Stroke treatments and more:

Stroke (334,631 reports)

Browse all side effects of Zinacef:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Stroke:

Stroke (2,376 drugs)

Browse all the conditions that are associated with Stroke:

Stroke (3,011 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on cefuroxime sodium (the active ingredients of Zinacef) and Zinacef (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.