Zioptan and Joint pain - a phase IV clinical study of FDA data

Summary:

Joint pain is reported as a side effect among people who take Zioptan (tafluprost), especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months also take Synthroid, and have High blood pressure.

The phase IV clinical study analyzes which people have Joint pain when taking Zioptan. It is created by eHealthMe based on reports of 2,491 people who have side effects when taking Zioptan from the FDA, and is updated regularly.

What is Zioptan?

Zioptan has active ingredients of tafluprost. It is often used in glaucoma. eHealthMe is studying from 2,512 Zioptan users. Check the latest studies of Zioptan.

What is Joint pain?

Joint pain is found to be associated with 3,331 drugs and 5,206 conditions by eHealthMe. Check the latest studies of Joint pain.



On Jul, 17, 2026

2,491 people reported to have side effects when taking Zioptan.
Among them, 33 people (1.32%) have Joint pain.

Could Zioptan cause Joint pain?

Among these 33 people:

How long have people been on Zioptan when they have Joint pain? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 66.67 %
  • 6 - 12 months: 33.33 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Joint pain when taking Zioptan? *

  • female: 57.14 %
  • male: 42.86 %

What is the age of people who have Joint pain when taking Zioptan? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 11.11 %
  • 50-59: 0.0 %
  • 60+: 88.89 %

What are other drugs people take besides Zioptan? *

  1. Humira: 3 people, 9.09%
  2. Alphagan P: 3 people, 9.09%
  3. Amlodipine: 3 people, 9.09%
  4. Synthroid: 3 people, 9.09%
  5. Tylenol: 2 people, 6.06%
  6. Methotrexate: 2 people, 6.06%
  7. Metformin: 2 people, 6.06%
  8. Losartan Potassium: 2 people, 6.06%
  9. Fish Oil: 2 people, 6.06%
  10. Tadalafil: 2 people, 6.06%

What are other side effects people have besides Joint pain? *

  1. Headache (pain in head): 5 people, 15.15%
  2. Arthropathy: 5 people, 15.15%
  3. Muscle Aches (muscle pain): 4 people, 12.12%
  4. Ocular Hyperaemia (an abnormally large amount of blood in eye): 3 people, 9.09%
  5. Pain: 3 people, 9.09%
  6. Chest Pain: 3 people, 9.09%
  7. Burning Sensation: 3 people, 9.09%
  8. Cough: 2 people, 6.06%
  9. Hypoaesthesia (reduced sense of touch or sensation): 2 people, 6.06%
  10. Itching: 2 people, 6.06%

What are the existing conditions these people have? *

  1. Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 2 people, 6.06%
  2. Normal Tension Glaucoma (a unique condition in which optic nerve damage and vision loss have occurred despite a normal pressure inside the eye): 2 people, 6.06%
  3. Dermatitis Atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder): 2 people, 6.06%
  4. High Blood Pressure: 2 people, 6.06%
  5. Sleep Disorder: 1 person, 3.03%
  6. Infection: 1 person, 3.03%
  7. Ankylosing Spondylitis (type of arthritis affecting the spine): 1 person, 3.03%
  8. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 1 person, 3.03%
  9. Dermatitis Allergic (inflammation of the skin due allergic reaction): 1 person, 3.03%
  10. Diabetes: 1 person, 3.03%

* Approximation only. Some reports may have incomplete information.

Do you take Zioptan and have Joint pain?

- Check whether Joint pain is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Zioptan:

Joint pain treatments and more:

How severe was Joint pain and when was it recovered:

Expand to all the drugs that have ingredients of tafluprost:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Zioptan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Joint pain:

Browse all the conditions that are associated with Joint pain:


How the study uses the data?

The study uses data from the FDA. It is based on tafluprost (the active ingredients of Zioptan) and Zioptan (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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