Zirabev and Fatigue - a phase IV clinical study of FDA data

Summary:

Fatigue is reported as a side effect among people who take Zirabev (bevacizumab-bvzr), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Zejula, and have Ovarian cancer.

The phase IV clinical study analyzes which people have Fatigue when taking Zirabev. It is created by eHealthMe based on reports of 614 people who have side effects when taking Zirabev from the FDA, and is updated regularly.

What is Zirabev?

Zirabev has active ingredients of bevacizumab-bvzr. eHealthMe is studying from 614 Zirabev users. Check the latest studies of Zirabev.

What is Fatigue?

Fatigue (feeling of tiredness) is found to be associated with 4,027 drugs and 6,380 conditions by eHealthMe. Check the latest studies of Fatigue.

On Jul, 10, 2026

614 people reported to have side effects when taking Zirabev.
Among them, 48 people (7.82%) have Fatigue.

Among these 48 people:

How long have people been on Zirabev when they have Fatigue? *

What is the gender of people who have Fatigue when taking Zirabev? *

female: 50 %
male: 50 %

What is the age of people who have Fatigue when taking Zirabev? *

What are other drugs people take besides Zirabev? *

What are other side effects people have besides Fatigue? *

High Blood Pressure: 20 people, 41.67%
Weight Decreased: 15 people, 31.25%
Neoplasm Progression (growth of tumour): 14 people, 29.17%
Drowsiness: 13 people, 27.08%
Malaise (a feeling of general discomfort or uneasiness): 12 people, 25.00%
Nausea (feeling of having an urge to vomit): 12 people, 25.00%
Constipation: 11 people, 22.92%
Pain: 11 people, 22.92%
Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 9 people, 18.75%
Nasopharyngitis (inflammation of the nasopharynx): 9 people, 18.75%

What are the existing conditions these people have? *

Ovarian Cancer (cancer of ovary): 10 people, 20.83%
Colon Cancer Metastatic (cancer of colon spreads to other part of body): 3 people, 6.25%
Hereditary Haemorrhagic Telangiectasia (hereditary -development of multiple abnormalities in the blood vessels): 3 people, 6.25%
Malignant Neoplasm Progression (cancer tumour came back): 3 people, 6.25%
Nosebleed (bleeding from nose): 3 people, 6.25%
Glioblastoma (most common and most aggressive malignant primary brain tumour in humans): 3 people, 6.25%
Angiodysplasia (small vascular malformation of the gut): 3 people, 6.25%
Ovarian Cancer Stage Iv: 2 people, 4.17%
Oligodendroglioma (a type of glioma that are believed to originate from the oligodendrocytes of the brain or from a glial precursor cell): 2 people, 4.17%
Malignant Glioma (cancerous tumour of brain a cancer tumour of uncertain origin that arises both in soft tissue and bone): 2 people, 4.17%

* Approximation only. Some reports may have incomplete information.

Do you take Zirabev and have Fatigue?

- Check whether Fatigue is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Zirabev:

Zirabev (614 reports)

Fatigue treatments and more:

Fatigue (967,537 reports)

Browse all side effects of Zirabev:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Fatigue:

Fatigue (4,027 drugs)

Browse all the conditions that are associated with Fatigue:

Fatigue (6,380 conditions)

Related publications that referenced our studies

Peel MM, Cooke M, Lewis-Peel HJ, Lea RA, Moyle W, "A randomized controlled trial of coenzyme Q 10 for fatigue in the late-onset sequelae of poliomyelitis", Complementary therapies in medicine, 2015 Dec .
Peel MM, Cooke M, Lewis-Peel HJ, Lea RA, Moyle W, "A randomized controlled trial of coenzyme Q 10 for fatigue in the late-onset sequelae of poliomyelitis", Complementary therapies in medicine, 2015 Dec .

How the study uses the data?

The study uses data from the FDA. It is based on bevacizumab-bvzr (the active ingredients of Zirabev) and Zirabev (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.