Zocor and Maculopathy - a phase IV clinical study of FDA data

Summary:

Maculopathy is reported as a side effect among people who take Zocor (simvastatin), especially for people who are male, 60+ old, have been taking the drug for 10+ years also take Lipitor, and have Prostatitis.

The phase IV clinical study analyzes which people have Maculopathy when taking Zocor. It is created by eHealthMe based on reports of 84,616 people who have side effects when taking Zocor from the FDA, and is updated regularly.

What is Zocor?

Zocor has active ingredients of simvastatin. It is often used in high blood cholesterol. eHealthMe is studying from 86,545 Zocor users. Check the latest studies of Zocor.

What is Maculopathy?

Maculopathy (a condition or disease of the macula, the small spot in the retina where vision is keenest) is found to be associated with 378 drugs and 730 conditions by eHealthMe. Check the latest studies of Maculopathy.



On Aug, 09, 2026

84,616 people reported to have side effects when taking Zocor.
Among them, 35 people (0.04%) have Maculopathy.

Could Zocor cause Maculopathy?

Among these 35 people:

How long have people been on Zocor when they have Maculopathy? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 40 %
  • 10+ years: 60 %

What is the gender of people who have Maculopathy when taking Zocor? *

  • female: 41.18 %
  • male: 58.82 %

What is the age of people who have Maculopathy when taking Zocor? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 3.45 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 20.69 %
  • 50-59: 13.79 %
  • 60+: 62.07 %

What are other drugs people take besides Zocor? *

  1. Lipitor: 13 people, 37.14%
  2. Zometa: 10 people, 28.57%
  3. Hytrin: 10 people, 28.57%
  4. Saw Palmetto: 10 people, 28.57%
  5. Aredia: 10 people, 28.57%
  6. Proscar: 10 people, 28.57%
  7. Aspirin: 8 people, 22.86%
  8. Vitamins: 8 people, 22.86%
  9. Elmiron: 7 people, 20.00%
  10. Ceftin: 6 people, 17.14%

What are other side effects people have besides Maculopathy? *

  1. Pain: 14 people, 40.00%
  2. Stress And Anxiety: 12 people, 34.29%
  3. Vision Blurred: 12 people, 34.29%
  4. Rashes (redness): 12 people, 34.29%
  5. Peripheral Vascular Disorder: 11 people, 31.43%
  6. Decreased Interest: 10 people, 28.57%
  7. Multiple Myeloma (cancer of the plasma cells): 10 people, 28.57%
  8. Bone Scan Abnormal: 10 people, 28.57%
  9. Lump In The Abdomen (an area of swelling or growth on abdomen): 10 people, 28.57%
  10. Plasma Cells Increased: 10 people, 28.57%

What are the existing conditions these people have? *

  1. Multiple Myeloma (cancer of the plasma cells): 10 people, 28.57%
  2. Prostatitis (inflammation of the prostate gland): 10 people, 28.57%
  3. Cystitis Interstitial (unknown cause characterized by bladder pain): 7 people, 20.00%
  4. Depression: 6 people, 17.14%
  5. Asthma: 5 people, 14.29%
  6. Fibromyalgia (a long-term condition which causes pain all over the body): 4 people, 11.43%
  7. Cardiac Disorder: 4 people, 11.43%
  8. Pain: 4 people, 11.43%
  9. Multiple Allergies (allergy to multiple agents): 3 people, 8.57%
  10. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 3 people, 8.57%

* Approximation only. Some reports may have incomplete information.

Do you take Zocor and have Maculopathy?

- Check whether Maculopathy is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Zocor:

Maculopathy treatments and more:

How severe was Maculopathy and when was it recovered:

Expand to all the drugs that have ingredients of simvastatin:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Zocor:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Maculopathy:

Browse all the conditions that are associated with Maculopathy:


How the study uses the data?

The study uses data from the FDA. It is based on simvastatin (the active ingredients of Zocor) and Zocor (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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