Zoladex and Neoplasm recurrence - a phase IV clinical study of FDA data

Summary:

Neoplasm recurrence is reported as a side effect among people who take Zoladex (goserelin acetate), especially for people who are female, 40-49 old, have been taking the drug for 1 - 2 years also take Tamoxifen Citrate, and have Breast cancer metastatic.

The phase IV clinical study analyzes which people have Neoplasm recurrence when taking Zoladex. It is created by eHealthMe based on reports of 13,593 people who have side effects when taking Zoladex from the FDA, and is updated regularly.

What is Zoladex?

Zoladex has active ingredients of goserelin acetate. It is often used in prostate cancer. eHealthMe is studying from 13,869 Zoladex users. Check the latest studies of Zoladex.

What is Neoplasm recurrence?

Neoplasm recurrence (reoccurrence of tumour) is found to be associated with 360 drugs and 495 conditions by eHealthMe. Check the latest studies of Neoplasm recurrence.

On Jul, 26, 2026

13,593 people reported to have side effects when taking Zoladex.
Among them, 14 people (0.1%) have Neoplasm recurrence.

Could Zoladex cause Neoplasm recurrence?

Among these 14 people:

How long have people been on Zoladex when they have Neoplasm recurrence? *

What is the gender of people who have Neoplasm recurrence when taking Zoladex? *

female: 100 %
male: 0.0 %

What is the age of people who have Neoplasm recurrence when taking Zoladex? *

What are other drugs people take besides Zoladex? *

What are other side effects people have besides Neoplasm recurrence? *

Malignant Neoplasm Progression (cancer tumour came back): 6 people, 42.86%
Neutrophil Count Decreased (less than normal number of neutrophil a type of blood cell): 4 people, 28.57%
Endometrial Hypertrophy (enlargement of uterine wall from the increase in size of its cells): 4 people, 28.57%
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 4 people, 28.57%
Anaphylaxis (serious allergic reaction that is rapid in onset and may cause death): 4 people, 28.57%
Blood Test Abnormal: 4 people, 28.57%
Fatigue (feeling of tiredness): 4 people, 28.57%
Fever: 3 people, 21.43%
Febrile Neutropenia (fever with reduced white blood cells): 3 people, 21.43%
Feeling Abnormal: 3 people, 21.43%

What are the existing conditions these people have? *

Breast Cancer Metastatic: 4 people, 28.57%
Bone Disorder: 3 people, 21.43%
Breast Cancer Female: 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Zoladex and have Neoplasm recurrence?

- Check whether Neoplasm recurrence is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Zoladex:

Zoladex (13,869 reports)

Browse all side effects of Zoladex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Neoplasm recurrence:

Neoplasm recurrence (361 drugs)

Browse all the conditions that are associated with Neoplasm recurrence:

Neoplasm recurrence (495 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on goserelin acetate (the active ingredients of Zoladex) and Zoladex (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.