Zoledronic acid and Bradycardia - a phase IV clinical study of FDA data

Summary:

Bradycardia is reported as a side effect among people who take Zoledronic acid (zoledronic acid), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Zoladex, and have Osteoporosis.

The phase IV clinical study analyzes which people have Bradycardia when taking Zoledronic acid. It is created by eHealthMe based on reports of 28,440 people who have side effects when taking Zoledronic acid from the FDA, and is updated regularly.

What is Zoledronic acid?

Zoledronic acid has active ingredients of zoledronic acid. eHealthMe is studying from 28,485 Zoledronic acid users. Check the latest studies of Zoledronic acid.

What is Bradycardia?

Bradycardia (abnormally slow heart action) is found to be associated with 1,930 drugs and 3,118 conditions by eHealthMe. Check the latest studies of Bradycardia.

On Jul, 15, 2026

28,440 people reported to have side effects when taking Zoledronic acid.
Among them, 59 people (0.21%) have Bradycardia.

Could Zoledronic acid cause Bradycardia?

Among these 59 people:

How long have people been on Zoledronic acid when they have Bradycardia? *

What is the gender of people who have Bradycardia when taking Zoledronic acid? *

female: 47.17 %
male: 52.83 %

What is the age of people who have Bradycardia when taking Zoledronic acid? *

What are other drugs people take besides Zoledronic acid? *

What are other side effects people have besides Bradycardia? *

Dizziness: 14 people, 23.73%
Arrhythmias (irregular heartbeat): 12 people, 20.34%
Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 11 people, 18.64%
Cardiac Arrest: 8 people, 13.56%
Hypotension (abnormally low blood pressure): 8 people, 13.56%
Pneumonia: 7 people, 11.86%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 7 people, 11.86%
Dyspnea (difficult or laboured breathing): 7 people, 11.86%
Malaise (a feeling of general discomfort or uneasiness): 6 people, 10.17%
Hypoglycemia (low blood sugar): 6 people, 10.17%

What are the existing conditions these people have? *

Osteoporosis (bones weak and more likely to break): 11 people, 18.64%
Multiple Myeloma (cancer of the plasma cells): 10 people, 16.95%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 9 people, 15.25%
Nausea (feeling of having an urge to vomit): 6 people, 10.17%
Prostate Cancer Metastatic: 6 people, 10.17%
High Blood Pressure: 5 people, 8.47%
Pain: 5 people, 8.47%
Breast Cancer: 5 people, 8.47%
Constipation: 4 people, 6.78%
Metastases To Bone (cancer spreads to bone): 4 people, 6.78%

* Approximation only. Some reports may have incomplete information.

Do you take Zoledronic acid and have Bradycardia?

- Check whether Bradycardia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Zoledronic acid:

Zoledronic acid (28,485 reports)

Bradycardia treatments and more:

Bradycardia (61,180 reports)

Browse all side effects of Zoledronic acid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Bradycardia:

Bradycardia (1,930 drugs)

Browse all the conditions that are associated with Bradycardia:

Bradycardia (3,118 conditions)

Related publications that referenced our studies

Schlumbrecht MP, Hehr K, "Cisplatin-induced bradycardia and the importance of the QT interval", Journal of Oncology Pharmacy Practice, 2015 Jan .
Oflaz MB, Kucukdurmaz Z, Guven AS, Karapinar H, Kaya A, Sancakdar E, Deveci K, Gul I, Erdem A, Cevit O, Icagasioglu FD, "Bradycardia seen in children with Crimean-Congo hemorrhagic fever", Vector-Borne and Zoonotic Diseases, 2013 Nov .
Schlumbrecht MP, Hehr K, "Cisplatin-induced bradycardia and the importance of the QT interval", Journal of Oncology Pharmacy Practice, 2015 Jan .
Oflaz MB, Kucukdurmaz Z, Guven AS, Karapinar H, Kaya A, Sancakdar E, Deveci K, Gul I, Erdem A, Cevit O, Icagasioglu FD, "Bradycardia seen in children with Crimean-Congo hemorrhagic fever", Vector-Borne and Zoonotic Diseases, 2013 Nov .

How the study uses the data?

The study uses data from the FDA. It is based on zoledronic acid (the active ingredients of Zoledronic acid) and Zoledronic acid (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.