Zoledronic and Joint dislocation - a phase IV clinical study of FDA data

Summary:

Joint dislocation is reported as a side effect among people who take Zoledronic (zoledronic acid), especially for people who are female, 60+ old, have been taking the drug for 2 - 5 years also take Calcium, and have Osteoporosis.

The phase IV clinical study analyzes which people have Joint dislocation when taking Zoledronic. It is created by eHealthMe based on reports of 29,760 people who have side effects when taking Zoledronic from the FDA, and is updated regularly.

What is Zoledronic?

Zoledronic has active ingredients of zoledronic acid. eHealthMe is studying from 29,812 Zoledronic users. Check the latest studies of Zoledronic.

What is Joint dislocation?

Joint dislocation (a joint position is changed from normal position) is found to be associated with 1,053 drugs and 913 conditions by eHealthMe. Check the latest studies of Joint dislocation.

On Nov, 29, 2025

29,760 people reported to have side effects when taking Zoledronic.
Among them, 30 people (0.1%) have Joint dislocation.

Could Zoledronic cause Joint dislocation?

Among these 30 people:

How long have people been on Zoledronic when they have Joint dislocation? *

What is the gender of people who have Joint dislocation when taking Zoledronic? *

female: 57.69 %
male: 42.31 %

What is the age of people who have Joint dislocation when taking Zoledronic? *

What are other drugs people take besides Zoledronic? *

What are other side effects people have besides Joint dislocation? *

Joint Pain: 11 people, 36.67%
Muscle Aches (muscle pain): 9 people, 30.00%
Pain In Extremity: 7 people, 23.33%
Musculoskeletal Pain (pain affects the bones, muscles, ligaments, tendons, and nerves): 7 people, 23.33%
Muscle Spasms (muscle contraction): 7 people, 23.33%
Pain: 6 people, 20.00%
Musculoskeletal Disorder (disease of the body's muscles, joints, tendons, ligaments and nerves): 5 people, 16.67%
Jaw Fracture: 5 people, 16.67%
Neck Pain: 5 people, 16.67%
Arrhythmias (irregular heartbeat): 5 people, 16.67%

What are the existing conditions these people have? *

Osteoporosis (bones weak and more likely to break): 14 people, 46.67%
Pain: 4 people, 13.33%
Multiple Myeloma (cancer of the plasma cells): 4 people, 13.33%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 4 people, 13.33%
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 2 people, 6.67%
Renal Cell Carcinoma (a kidney cancer): 2 people, 6.67%
Osteoporosis Post-Menopausal (weak bone with possibility to break after stopped menstrual cycles): 2 people, 6.67%
Oedema Peripheral (superficial swelling): 2 people, 6.67%
Breast Cancer Female: 2 people, 6.67%
Hypocalcaemia (levels of calcium in blood serum are abnormally low): 2 people, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Zoledronic and have Joint dislocation?

- Check whether Joint dislocation is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Zoledronic:

Zoledronic (29,812 reports)

Browse all side effects of Zoledronic:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Joint dislocation:

Joint dislocation (1,053 drugs)

Browse all the conditions that are associated with Joint dislocation:

Joint dislocation (913 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on zoledronic acid (the active ingredients of Zoledronic) and Zoledronic (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.