Zoloft and Ammonia increased - a phase IV clinical study of FDA data

Summary:

Ammonia increased is reported as a side effect among people who take Zoloft (sertraline hydrochloride), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Lamictal, and have Convulsion.

The phase IV clinical study analyzes which people have Ammonia increased when taking Zoloft. It is created by eHealthMe based on reports of 128,159 people who have side effects when taking Zoloft from the FDA, and is updated regularly.

What is Zoloft?

Zoloft has active ingredients of sertraline hydrochloride. It is often used in depression. eHealthMe is studying from 138,798 Zoloft users. Check the latest studies of Zoloft.

What is Ammonia increased?

Ammonia increased is found to be associated with 559 drugs and 763 conditions by eHealthMe. Check the latest studies of Ammonia increased.

On Jul, 07, 2026

128,159 people reported to have side effects when taking Zoloft.
Among them, 80 people (0.06%) have Ammonia increased.

Among these 80 people:

How long have people been on Zoloft when they have Ammonia increased? *

What is the gender of people who have Ammonia increased when taking Zoloft? *

female: 50.63 %
male: 49.37 %

What is the age of people who have Ammonia increased when taking Zoloft? *

What are other drugs people take besides Zoloft? *

Lamictal: 16 people, 20.00%
Keppra: 15 people, 18.75%
Folic Acid: 13 people, 16.25%
Levetiracetam: 13 people, 16.25%
Alprazolam: 13 people, 16.25%
Lamotrigine: 12 people, 15.00%
Acetaminophen And Hydrocodone Bitartrate: 12 people, 15.00%
Coumadin: 11 people, 13.75%
Lasix: 9 people, 11.25%
Zantac: 6 people, 7.50%

What are other side effects people have besides Ammonia increased? *

Diarrhea: 23 people, 28.75%
Insomnia (sleeplessness): 20 people, 25.00%
Fever: 20 people, 25.00%
Constipation: 19 people, 23.75%
Respiratory Distress (difficulty in breathing): 17 people, 21.25%
Nausea (feeling of having an urge to vomit): 17 people, 21.25%
Irritability: 16 people, 20.00%
Hepatic Encephalopathy (spectrum of neuropsychiatric abnormalities in patients with liver failure): 15 people, 18.75%
Failure To Thrive (inadequate weight gain and physical growth in children): 15 people, 18.75%
Fatigue (feeling of tiredness): 14 people, 17.50%

What are the existing conditions these people have? *

Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 14 people, 17.50%
Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 5 people, 6.25%
Hepatitis C: 5 people, 6.25%
Acromegaly (body produces too much growth hormone, leading to excess growth of body tissues): 3 people, 3.75%
Pulmonary Hypertension (increase in blood pressure in the lung artery): 3 people, 3.75%
High Blood Cholesterol: 3 people, 3.75%
Weight Loss: 2 people, 2.50%
Dementia Alzheimer's Type (loss of mental ability with alzheimer's symptom): 2 people, 2.50%
Constipation: 2 people, 2.50%
Pain: 2 people, 2.50%

* Approximation only. Some reports may have incomplete information.

Do you take Zoloft and have Ammonia increased?

- Check whether Ammonia increased is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Zoloft:

Zoloft (138,798 reports)

Browse all side effects of Zoloft:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Ammonia increased:

Ammonia increased (559 drugs)

Browse all the conditions that are associated with Ammonia increased:

Ammonia increased (763 conditions)

Related publications that referenced our studies

Izgi C, Erdem G, Mansuroglu D, Kurtoglu N, Kara M, Gunesdogdu F, "Severe hypokalemia probably associated with sertraline use", Annals of Pharmacotherapy, 2014 Jan .
Izgi C, Erdem G, Mansuroglu D, Kurtoglu N, Kara M, Gunesdogdu F, "Severe hypokalemia probably associated with sertraline use", Annals of Pharmacotherapy, 2014 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on sertraline hydrochloride (the active ingredients of Zoloft) and Zoloft (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.