Zoloft and Bedwetting - a phase IV clinical study of FDA data

Summary:

Bedwetting is reported as a side effect among people who take Zoloft (sertraline hydrochloride), especially for people who are female, 10-19 old, have been taking the drug for 1 - 2 years also take Xyrem, and have Narcolepsy.

The phase IV clinical study analyzes which people have Bedwetting when taking Zoloft. It is created by eHealthMe based on reports of 128,159 people who have side effects when taking Zoloft from the FDA, and is updated regularly.

What is Zoloft?

Zoloft has active ingredients of sertraline hydrochloride. It is often used in depression. eHealthMe is studying from 138,801 Zoloft users. Check the latest studies of Zoloft.

What is Bedwetting?

Bedwetting is found to be associated with 468 drugs and 864 conditions by eHealthMe. Check the latest studies of Bedwetting.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

128,159 people reported to have side effects when taking Zoloft.
Among them, 96 people (0.07%) have Bedwetting.

Among these 96 people:

How long have people been on Zoloft when they have Bedwetting? *

What is the gender of people who have Bedwetting when taking Zoloft? *

female: 57.61 %
male: 42.39 %

What is the age of people who have Bedwetting when taking Zoloft? *

What are other drugs people take besides Zoloft? *

What are other side effects people have besides Bedwetting? *

Nausea And Vomiting: 17 people, 17.71%
Drowsiness: 11 people, 11.46%
Weight Increased: 10 people, 10.42%
Tachypnea: 10 people, 10.42%
Weakness: 10 people, 10.42%
Pneumonia: 10 people, 10.42%
Otitis Media (inflammation of the middle ear): 9 people, 9.38%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 9 people, 9.38%
Sleep Walking (walking during sleep): 9 people, 9.38%
Speech Disorder: 9 people, 9.38%

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 30 people, 31.25%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 23 people, 23.96%
Drowsiness: 9 people, 9.38%
High Blood Pressure: 7 people, 7.29%
Obsessive-Compulsive Disorder (an anxiety disorder characterized by intrusive thoughts that produce uneasiness, apprehension, fear, or worry;): 7 people, 7.29%
Pelvic Pain: 5 people, 5.21%
Pain: 5 people, 5.21%
Hypochondria (health phobia or health anxiety): 5 people, 5.21%
Attention Deficit Hyperactivity Disorder (a chronic condition including attention difficulty, hyperactivity, and impulsiveness): 5 people, 5.21%
Discomfort: 5 people, 5.21%

* Approximation only. Some reports may have incomplete information.

Do you take Zoloft and have Bedwetting?

- Check whether Bedwetting is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Zoloft:

Zoloft (138,801 reports)

Bedwetting treatments and more:

Bedwetting (6,093 reports)

Browse all side effects of Zoloft:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Bedwetting:

Bedwetting (468 drugs)

Browse all the conditions that are associated with Bedwetting:

Bedwetting (864 conditions)

Related publications that referenced our studies

Izgi C, Erdem G, Mansuroglu D, Kurtoglu N, Kara M, Gunesdogdu F, "Severe hypokalemia probably associated with sertraline use", Annals of Pharmacotherapy, 2014 Jan .
Izgi C, Erdem G, Mansuroglu D, Kurtoglu N, Kara M, Gunesdogdu F, "Severe hypokalemia probably associated with sertraline use", Annals of Pharmacotherapy, 2014 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on sertraline hydrochloride (the active ingredients of Zoloft) and Zoloft (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.