Zoloft and Prolonged labor - a phase IV clinical study of FDA data

Summary:

Prolonged labor is reported as a side effect among people who take Zoloft (sertraline hydrochloride), especially for people who are 20-29 old, have been taking the drug for 1 - 2 years also take Risperdal, and have Bipolar disorder.

The phase IV clinical study analyzes which people have Prolonged labor when taking Zoloft. It is created by eHealthMe based on reports of 128,159 people who have side effects when taking Zoloft from the FDA, and is updated regularly.

What is Zoloft?

Zoloft has active ingredients of sertraline hydrochloride. It is often used in depression. eHealthMe is studying from 138,798 Zoloft users. Check the latest studies of Zoloft.

What is Prolonged labor?

Prolonged labor is found to be associated with 58 drugs and 182 conditions by eHealthMe. Check the latest studies of Prolonged labor.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 29, 2026

128,159 people reported to have side effects when taking Zoloft.
Among them, 13 people (0.01%) have Prolonged labor.

Among these 13 people:

How long have people been on Zoloft when they have Prolonged labor? *

What is the age of people who have Prolonged labor when taking Zoloft? *

What are other drugs people take besides Zoloft? *

What are other side effects people have besides Prolonged labor? *

Nausea (feeling of having an urge to vomit): 7 people, 53.85%
Maternal Exposure During Pregnancy (use of substance during pregnancy): 6 people, 46.15%
Live Birth: 3 people, 23.08%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 23.08%
Dizziness: 2 people, 15.38%
Normal Newborn: 2 people, 15.38%
Gestational Diabetes (diabetes in pregnancy): 2 people, 15.38%
Foot Fracture: 2 people, 15.38%
Headache (pain in head): 2 people, 15.38%
Scab (a hard coating on the skin formed during the wound healing): 2 people, 15.38%

What are the existing conditions these people have? *

Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 6 people, 46.15%
Bipolar Disorder (mood disorder): 6 people, 46.15%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 23.08%
Sleep Disorder: 1 person, 7.69%
Restless Leg Syndrome (a powerful urge to move your legs): 1 person, 7.69%
Psoriasis (immune-mediated disease that affects the skin): 1 person, 7.69%
Postpartum Depression (depression suffered by a mother following childbirth): 1 person, 7.69%
Pain In Extremity: 1 person, 7.69%
Neuropathy Peripheral (surface nerve damage): 1 person, 7.69%
Mood Swings (an extreme or rapid change in mood): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Zoloft and have Prolonged labor?

- Check whether Prolonged labor is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Zoloft:

Zoloft (138,798 reports)

Browse all side effects of Zoloft:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Prolonged labor:

Prolonged labor (58 drugs)

Browse all the conditions that are associated with Prolonged labor:

Prolonged labor (182 conditions)

Related publications that referenced our studies

Izgi C, Erdem G, Mansuroglu D, Kurtoglu N, Kara M, Gunesdogdu F, "Severe hypokalemia probably associated with sertraline use", Annals of Pharmacotherapy, 2014 Jan .
Izgi C, Erdem G, Mansuroglu D, Kurtoglu N, Kara M, Gunesdogdu F, "Severe hypokalemia probably associated with sertraline use", Annals of Pharmacotherapy, 2014 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on sertraline hydrochloride (the active ingredients of Zoloft) and Zoloft (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.