Zoloft and Screaming - a phase IV clinical study of FDA data

Summary:

Screaming is reported as a side effect among people who take Zoloft (sertraline hydrochloride), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Seroquel, and have Sleep disorder.

The phase IV clinical study analyzes which people have Screaming when taking Zoloft. It is created by eHealthMe based on reports of 128,159 people who have side effects when taking Zoloft from the FDA, and is updated regularly.

What is Zoloft?

Zoloft has active ingredients of sertraline hydrochloride. It is often used in depression. eHealthMe is studying from 138,788 Zoloft users. Check the latest studies of Zoloft.

What is Screaming?

Screaming (a long loud piercing cry) is found to be associated with 650 drugs and 771 conditions by eHealthMe. Check the latest studies of Screaming.

On Nov, 29, 2025

128,159 people reported to have side effects when taking Zoloft.
Among them, 127 people (0.1%) have Screaming.

Among these 127 people:

* Approximation only. Some reports may have incomplete information.

Do you take Zoloft and have Screaming?

- Check whether Screaming is associated with a drug or a condition (FREE)
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Zoloft:

Zoloft (138,788 reports)

Screaming treatments and more:

Screaming (7,292 reports)

How severe was Screaming and when was it recovered:

Screaming in Zoloft

Expand to all the drugs that have ingredients of sertraline hydrochloride:

Screaming and drugs with ingredients of sertraline hydrochloride

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Common Zoloft side effects:

Zoloft side effect: Nausea (feeling of having an urge to vomit) (9,471 reports)
Zoloft side effect: Headache (pain in head) (7,890 reports)

Browse all side effects of Zoloft:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common drugs associated with Screaming:

Browse all the drugs that are associated with Screaming:

Screaming (650 drugs)

Common conditions associated with Screaming:

Antidepressant therapy: 368 reports
Pain: 260 reports
Attention deficit disorder with hyperactivity (addh): 239 reports
Smoking and smokeless tobacco: 226 reports
Parkinson's disease: 225 reports
Asthma: 222 reports
Chronic asthma: 221 reports
Feeling uptight: 173 reports
Flu: 143 reports
Sleep issues: 133 reports

Browse all the conditions that are associated with Screaming:

Screaming (771 conditions)

Drugs similar to Zoloft and Screaming :

Related publications that referenced our studies

Izgi C, Erdem G, Mansuroglu D, Kurtoglu N, Kara M, Gunesdogdu F, "Severe hypokalemia probably associated with sertraline use", Annals of Pharmacotherapy, 2014 Jan .
Izgi C, Erdem G, Mansuroglu D, Kurtoglu N, Kara M, Gunesdogdu F, "Severe hypokalemia probably associated with sertraline use", Annals of Pharmacotherapy, 2014 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on sertraline hydrochloride (the active ingredients of Zoloft) and Zoloft (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.