Zoloft and Ttp - a phase IV clinical study of FDA data

Summary:

Ttp is reported as a side effect among people who take Zoloft (sertraline hydrochloride), especially for people who are female, 60+ old, also take Plaquenil, and have Breast cancer metastatic.

The phase IV clinical study analyzes which people have Ttp when taking Zoloft. It is created by eHealthMe based on reports of 128,159 people who have side effects when taking Zoloft from the FDA, and is updated regularly.

What is Zoloft?

Zoloft has active ingredients of sertraline hydrochloride. It is often used in depression. eHealthMe is studying from 138,792 Zoloft users. Check the latest studies of Zoloft.

What is Ttp?

Ttp is found to be associated with 940 drugs and 820 conditions by eHealthMe. Check the latest studies of Ttp.

On Dec, 20, 2025

128,159 people reported to have side effects when taking Zoloft.
Among them, 43 people (0.03%) have Ttp.

Among these 43 people:

What is the gender of people who have Ttp when taking Zoloft? *

female: 81.4 %
male: 18.6 %

What is the age of people who have Ttp when taking Zoloft? *

What are other drugs people take besides Zoloft? *

What are other side effects people have besides Ttp? *

Weakness: 13 people, 30.23%
Acute Kidney Failure: 13 people, 30.23%
Anaemia (lack of blood): 13 people, 30.23%
Fatigue (feeling of tiredness): 12 people, 27.91%
Red Blood Cell Schistocytes Present: 11 people, 25.58%
Pain: 11 people, 25.58%
Nausea (feeling of having an urge to vomit): 11 people, 25.58%
Nausea And Vomiting: 10 people, 23.26%
Dyspnea (difficult or laboured breathing): 10 people, 23.26%
Headache (pain in head): 10 people, 23.26%

What are the existing conditions these people have? *

Breast Cancer: 8 people, 18.60%
Breast Cancer Metastatic: 8 people, 18.60%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 7 people, 16.28%
Pain: 5 people, 11.63%
Ill-Defined Disorder: 3 people, 6.98%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 3 people, 6.98%
Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 2 people, 4.65%
Muscle Spasms (muscle contraction): 2 people, 4.65%
Bone Marrow Conditioning Regimen: 2 people, 4.65%
Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 2 people, 4.65%

* Approximation only. Some reports may have incomplete information.

Do you take Zoloft and have Ttp?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Zoloft:

Zoloft (138,792 reports)

Ttp treatments and more:

Ttp (6,447 reports)

Browse all side effects of Zoloft:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Ttp:

Ttp (940 drugs)

Browse all the conditions that are associated with Ttp:

Ttp (820 conditions)

Drugs similar to Zoloft and Ttp :

Related publications that referenced our studies

Izgi C, Erdem G, Mansuroglu D, Kurtoglu N, Kara M, Gunesdogdu F, "Severe hypokalemia probably associated with sertraline use", Annals of Pharmacotherapy, 2014 Jan .
Izgi C, Erdem G, Mansuroglu D, Kurtoglu N, Kara M, Gunesdogdu F, "Severe hypokalemia probably associated with sertraline use", Annals of Pharmacotherapy, 2014 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on sertraline hydrochloride (the active ingredients of Zoloft) and Zoloft (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.