Zonegran and Cerebral disorder - a phase IV clinical study of FDA data

Summary:

Cerebral disorder is reported as a side effect among people who take Zonegran (zonisamide), especially for people who are male, 0-1 old, have been taking the drug for 6 - 12 months also take Keppra, and have Sleep disorder.

The phase IV clinical study analyzes which people have Cerebral disorder when taking Zonegran. It is created by eHealthMe based on reports of 5,875 people who have side effects when taking Zonegran from the FDA, and is updated regularly.

What is Zonegran?

Zonegran has active ingredients of zonisamide. It is often used in epilepsy. eHealthMe is studying from 6,211 Zonegran users. Check the latest studies of Zonegran.

What is Cerebral disorder?

Cerebral disorder (brain disease) is found to be associated with 656 drugs and 683 conditions by eHealthMe. Check the latest studies of Cerebral disorder.

On Jul, 11, 2026

5,875 people reported to have side effects when taking Zonegran.
Among them, 16 people (0.27%) have Cerebral disorder.

Among these 16 people:

How long have people been on Zonegran when they have Cerebral disorder? *

What is the gender of people who have Cerebral disorder when taking Zonegran? *

female: 35.71 %
male: 64.29 %

What is the age of people who have Cerebral disorder when taking Zonegran? *

What are other drugs people take besides Zonegran? *

What are other side effects people have besides Cerebral disorder? *

Hydrocephalus (water on the brain): 7 people, 43.75%
Hypotonia (low muscle tone): 7 people, 43.75%
Increased Head Circumference (measured distance around the widest part of the skull is larger than expected for the child's age): 7 people, 43.75%
Low Set Ears (depressed positioning of the pinna (outer ear )): 7 people, 43.75%
Cytogenetic Abnormality: 7 people, 43.75%
Autism Spectrum Disorder (developmental disabilities that can cause significant social, communication and behavioural challenges): 6 people, 37.50%
Aggression: 6 people, 37.50%
Dysmorphism (difference of body structure that is suggestive of a congenital disorder): 6 people, 37.50%
Motormental Retardation (a slowing-down of thought and a reduction of physical work): 6 people, 37.50%
Fatigue (feeling of tiredness): 5 people, 31.25%

What are the existing conditions these people have? *

Sleep Disorder: 3 people, 18.75%
Stress And Anxiety: 2 people, 12.50%
Restless Leg Syndrome (a powerful urge to move your legs): 2 people, 12.50%
Nausea And Vomiting: 2 people, 12.50%
Depression: 2 people, 12.50%
Asthma: 2 people, 12.50%
Parkinson's Disease: 1 person, 6.25%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 1 person, 6.25%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Zonegran and have Cerebral disorder?

- Check whether Cerebral disorder is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Zonegran:

Zonegran (6,211 reports)

Browse all side effects of Zonegran:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Cerebral disorder:

Cerebral disorder (656 drugs)

Browse all the conditions that are associated with Cerebral disorder:

Cerebral disorder (683 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on zonisamide (the active ingredients of Zonegran) and Zonegran (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.