Zonisamide and Liver function test abnormal - a phase IV clinical study of FDA data

Summary:

Liver function test abnormal is reported as a side effect among people who take Zonisamide (zonisamide), especially for people who are female, 40-49 old, have been taking the drug for < 1 month also take Proair Hfa, and have Hypersensitivity.

The phase IV clinical study analyzes which people have Liver function test abnormal when taking Zonisamide. It is created by eHealthMe based on reports of 11,045 people who have side effects when taking Zonisamide from the FDA, and is updated regularly.

What is Zonisamide?

Zonisamide has active ingredients of zonisamide. It is often used in epilepsy. eHealthMe is studying from 11,445 Zonisamide users. Check the latest studies of Zonisamide.

What is Liver function test abnormal?

Liver function test abnormal is found to be associated with 1,493 drugs and 1,963 conditions by eHealthMe. Check the latest studies of Liver function test abnormal.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

11,045 people reported to have side effects when taking Zonisamide.
Among them, 12 people (0.11%) have Liver function test abnormal.

Could Zonisamide cause Liver function test abnormal?

Among these 12 people:

How long have people been on Zonisamide when they have Liver function test abnormal? *

What is the gender of people who have Liver function test abnormal when taking Zonisamide? *

female: 90.91 %
male: 9.09 %

What is the age of people who have Liver function test abnormal when taking Zonisamide? *

What are other drugs people take besides Zonisamide? *

What are other side effects people have besides Liver function test abnormal? *

Fever: 4 people, 33.33%
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 3 people, 25.00%
Arrhythmias (irregular heartbeat): 2 people, 16.67%
Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down): 2 people, 16.67%
Carnitine Decreased: 2 people, 16.67%
Myoglobin Urine Present: 2 people, 16.67%
Lymph Follicular Hypertrophy (an increase in the size of the lymph node follicles): 2 people, 16.67%
Disseminated Intravascular Coagulation (systemic activation of blood coagulation): 2 people, 16.67%
Drug Rash With Eosinophilia And Systemic Symptoms (adverse drug reactions with rash): 2 people, 16.67%
White Blood Cell Count Decreased: 1 person, 8.33%

What are the existing conditions these people have? *

Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 2 people, 16.67%
Productive Cough: 2 people, 16.67%
Pain: 2 people, 16.67%
Neurofibroma (non-cancerous tumours that grow on nerves throughout the body): 2 people, 16.67%
Nausea (feeling of having an urge to vomit): 2 people, 16.67%
Muscle Tightness: 2 people, 16.67%
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 2 people, 16.67%
Dyspnea (difficult or laboured breathing): 2 people, 16.67%
Hypersensitivity: 2 people, 16.67%
Heart Attack: 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Zonisamide and have Liver function test abnormal?

- Check whether Liver function test abnormal is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Zonisamide:

Zonisamide (11,445 reports)

Browse all side effects of Zonisamide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Liver function test abnormal:

Liver function test abnormal (1,493 drugs)

Browse all the conditions that are associated with Liver function test abnormal:

Liver function test abnormal (1,963 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on zonisamide (the active ingredients of Zonisamide) and Zonisamide (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.