Zopiclone and White blood cell count abnormal - a phase IV clinical study of FDA data

Summary:

White blood cell count abnormal is reported as a side effect among people who take Zopiclone (eszopiclone), especially for people who are female, 60+ old, also take Mirtazapine, and have Thyroid diseases.

The phase IV clinical study analyzes which people have White blood cell count abnormal when taking Zopiclone. It is created by eHealthMe based on reports of 52,551 people who have side effects when taking Zopiclone from the FDA, and is updated regularly.

What is Zopiclone?

Zopiclone has active ingredients of eszopiclone. It is often used in insomnia. eHealthMe is studying from 54,331 Zopiclone users. Check the latest studies of Zopiclone.

What is White blood cell count abnormal?

White blood cell count abnormal is found to be associated with 555 drugs and 841 conditions by eHealthMe. Check the latest studies of White blood cell count abnormal.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 29, 2026

52,551 people reported to have side effects when taking Zopiclone.
Among them, 28 people (0.05%) have White blood cell count abnormal.

Could Zopiclone cause White blood cell count abnormal?

Among these 28 people:

What is the gender of people who have White blood cell count abnormal when taking Zopiclone? *

female: 80.77 %
male: 19.23 %

What is the age of people who have White blood cell count abnormal when taking Zopiclone? *

What are other drugs people take besides Zopiclone? *

What are other side effects people have besides White blood cell count abnormal? *

Pain: 18 people, 64.29%
Blood Albumin Abnormal: 15 people, 53.57%
Haemoglobin Abnormal: 15 people, 53.57%
Neutrophil Count Abnormal (abnormal number of neutrophil a type of blood cell): 14 people, 50.00%
Pulmonary Mass: 14 people, 50.00%
Joint Pain: 13 people, 46.43%
Dyspnea (difficult or laboured breathing): 13 people, 46.43%
Chest Wall Mass: 13 people, 46.43%
Chest Pain: 13 people, 46.43%
Glomerular Filtration Rate Increased: 13 people, 46.43%

What are the existing conditions these people have? *

Thyroid Diseases: 6 people, 21.43%
Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 5 people, 17.86%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 10.71%
Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 2 people, 7.14%
Hyperthyroidism (over activity of the thyroid gland): 2 people, 7.14%
Dyslipidaemia (abnormal amount of lipids): 2 people, 7.14%
Lung Adenocarcinoma Stage Iv (the cancer has spread to other organs of the body, such as the other lung, brain, or liver): 1 person, 3.57%
Dry Mouth: 1 person, 3.57%
Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 1 person, 3.57%
Chest Pain: 1 person, 3.57%

* Approximation only. Some reports may have incomplete information.

Do you take Zopiclone and have White blood cell count abnormal?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Zopiclone:

Zopiclone (54,331 reports)

Browse all side effects of Zopiclone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with White blood cell count abnormal:

White blood cell count abnormal (555 drugs)

Browse all the conditions that are associated with White blood cell count abnormal:

White blood cell count abnormal (841 conditions)

Related publications that referenced our studies

Lai SW, Lai HC, Lin CL, Liao KF, "Zopiclone use associated with increased risk of acute pancreatitis: a case–control study in Taiwan", International journal of clinical practice, 2015 Nov .
Lai SW, Lai HC, Lin CL, Liao KF, "Zopiclone use associated with increased risk of acute pancreatitis: a case–control study in Taiwan", International journal of clinical practice, 2015 Nov .

How the study uses the data?

The study uses data from the FDA. It is based on eszopiclone (the active ingredients of Zopiclone) and Zopiclone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.