Zorvolex and Fatigue - a phase IV clinical study of FDA data

Summary:

Fatigue is reported as a side effect among people who take Zorvolex (diclofenac), especially for people who are female, 50-59 old, have been taking the drug for < 1 month also take Cellcept, and have Rheumatoid arthritis.

The phase IV clinical study analyzes which people have Fatigue when taking Zorvolex. It is created by eHealthMe based on reports of 507 people who have side effects when taking Zorvolex from the FDA, and is updated regularly.

What is Zorvolex?

Zorvolex has active ingredients of diclofenac. It is often used in arthritis. eHealthMe is studying from 678 Zorvolex users. Check the latest studies of Zorvolex.

What is Fatigue?

Fatigue (feeling of tiredness) is found to be associated with 4,027 drugs and 6,379 conditions by eHealthMe. Check the latest studies of Fatigue.

On Jul, 13, 2026

507 people reported to have side effects when taking Zorvolex.
Among them, 16 people (3.16%) have Fatigue.

Among these 16 people:

How long have people been on Zorvolex when they have Fatigue? *

What is the gender of people who have Fatigue when taking Zorvolex? *

female: 68.75 %
male: 31.25 %

What is the age of people who have Fatigue when taking Zorvolex? *

What are other drugs people take besides Zorvolex? *

What are other side effects people have besides Fatigue? *

Drug Ineffective: 4 people, 25.00%
Nausea (feeling of having an urge to vomit): 4 people, 25.00%
Weakness: 4 people, 25.00%
Sinusitis (inflammation of sinus): 3 people, 18.75%
Hypoaesthesia (reduced sense of touch or sensation): 3 people, 18.75%
Malaise (a feeling of general discomfort or uneasiness): 3 people, 18.75%
Headache (pain in head): 3 people, 18.75%
Chest Pain: 2 people, 12.50%
Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 2 people, 12.50%
Pain In Extremity: 2 people, 12.50%

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 4 people, 25.00%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 2 people, 12.50%
Hepatitis C: 2 people, 12.50%
Stress And Anxiety: 1 person, 6.25%
Hypotension (abnormally low blood pressure): 1 person, 6.25%
Autonomic Neuropathy (malfunction of the autonomic nervous system (ans)): 1 person, 6.25%
Breast Cancer: 1 person, 6.25%
Dizziness: 1 person, 6.25%
Fainting (loss of consciousness and postural tone): 1 person, 6.25%
Heart Attack: 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Zorvolex and have Fatigue?

- Check whether Fatigue is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Zorvolex:

Zorvolex (678 reports)

Fatigue treatments and more:

Fatigue (967,537 reports)

Browse all side effects of Zorvolex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Fatigue:

Fatigue (4,027 drugs)

Browse all the conditions that are associated with Fatigue:

Fatigue (6,379 conditions)

Related publications that referenced our studies

Peel MM, Cooke M, Lewis-Peel HJ, Lea RA, Moyle W, "A randomized controlled trial of coenzyme Q 10 for fatigue in the late-onset sequelae of poliomyelitis", Complementary therapies in medicine, 2015 Dec .
Peel MM, Cooke M, Lewis-Peel HJ, Lea RA, Moyle W, "A randomized controlled trial of coenzyme Q 10 for fatigue in the late-onset sequelae of poliomyelitis", Complementary therapies in medicine, 2015 Dec .

How the study uses the data?

The study uses data from the FDA. It is based on diclofenac (the active ingredients of Zorvolex) and Zorvolex (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.