Zyban and Serum sickness - a phase IV clinical study of FDA data

Summary:

Serum sickness is reported as a side effect among people who take Zyban (bupropion hydrochloride), especially for people who are female, 30-39 old, have been taking the drug for < 1 month also take Ibuprofen,.

The phase IV clinical study analyzes which people have Serum sickness when taking Zyban. It is created by eHealthMe based on reports of 7,776 people who have side effects when taking Zyban from the FDA, and is updated regularly.

What is Zyban?

Zyban has active ingredients of bupropion hydrochloride. It is often used in quit smoking. eHealthMe is studying from 8,029 Zyban users. Check the latest studies of Zyban.

What is Serum sickness?

Serum sickness (hypersensitivity reaction that results from the injection of heterologous or foreign protein or serum) is found to be associated with 273 drugs and 488 conditions by eHealthMe. Check the latest studies of Serum sickness.

On Jul, 20, 2026

7,776 people reported to have side effects when taking Zyban.
Among them, 54 people (0.69%) have Serum sickness.

Among these 54 people:

How long have people been on Zyban when they have Serum sickness? *

What is the gender of people who have Serum sickness when taking Zyban? *

female: 62.26 %
male: 37.74 %

What is the age of people who have Serum sickness when taking Zyban? *

What are other drugs people take besides Zyban? *

Ibuprofen: 5 people, 9.26%
Temazepam: 4 people, 7.41%
Ranitidine Hydrochloride: 4 people, 7.41%
Metronidazole: 4 people, 7.41%
Nexium: 2 people, 3.70%
Lansoprazole: 2 people, 3.70%
Prednisone: 1 person, 1.85%
Paxil: 1 person, 1.85%
Nicotine: 1 person, 1.85%
Motrin: 1 person, 1.85%

What are other side effects people have besides Serum sickness? *

Joint Pain: 34 people, 62.96%
Itching: 19 people, 35.19%
Muscle Aches (muscle pain): 15 people, 27.78%
Fever: 14 people, 25.93%
Joint Swelling: 10 people, 18.52%
Difficulty In Walking: 8 people, 14.81%
Oedema Upper Limb (swelling of arm): 7 people, 12.96%
Rash Erythematous (redness of the skin): 6 people, 11.11%
Chills (felling of cold): 6 people, 11.11%
Malaise (a feeling of general discomfort or uneasiness): 6 people, 11.11%

* Approximation only. Some reports may have incomplete information.

Do you take Zyban and have Serum sickness?

- Check whether Serum sickness is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Zyban:

Zyban (8,029 reports)

Serum sickness treatments and more:

Serum sickness (3,679 reports)

Browse all side effects of Zyban:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Serum sickness:

Serum sickness (273 drugs)

Browse all the conditions that are associated with Serum sickness:

Serum sickness (488 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on bupropion hydrochloride (the active ingredients of Zyban) and Zyban (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.