Zykadia and Chest pain - a phase IV clinical study of FDA data

Summary:

Chest pain is reported as a side effect among people who take Zykadia (ceritinib), especially for people who are female, 50-59 old, have been taking the drug for 1 - 6 months also take Compazine, and have Lung cancer - non-small cell.

The phase IV clinical study analyzes which people have Chest pain when taking Zykadia. It is created by eHealthMe based on reports of 2,091 people who have side effects when taking Zykadia from the FDA, and is updated regularly.

What is Zykadia?

Zykadia has active ingredients of ceritinib. eHealthMe is studying from 2,091 Zykadia users. Check the latest studies of Zykadia.

What is Chest pain?

Chest pain is found to be associated with 3,459 drugs and 4,888 conditions by eHealthMe. Check the latest studies of Chest pain.



On Jul, 26, 2026

2,091 people reported to have side effects when taking Zykadia.
Among them, 44 people (2.1%) have Chest pain.

Could Zykadia cause Chest pain?

Among these 44 people:

How long have people been on Zykadia when they have Chest pain? *

  • < 1 month: 42.86 %
  • 1 - 6 months: 50.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 7.14 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Chest pain when taking Zykadia? *

  • female: 52.27 %
  • male: 47.73 %

What is the age of people who have Chest pain when taking Zykadia? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 14.71 %
  • 40-49: 17.65 %
  • 50-59: 47.06 %
  • 60+: 20.59 %

What are other drugs people take besides Zykadia? *

  1. Zofran: 2 people, 4.55%
  2. Xalkori: 2 people, 4.55%
  3. Calcium: 2 people, 4.55%
  4. Compazine: 2 people, 4.55%
  5. Zyrtec: 1 person, 2.27%
  6. Lipitor: 1 person, 2.27%
  7. Augmentin: 1 person, 2.27%
  8. Cymbalta: 1 person, 2.27%
  9. Eliquis: 1 person, 2.27%
  10. Fish Oil: 1 person, 2.27%

What are other side effects people have besides Chest pain? *

  1. Diarrhea: 14 people, 31.82%
  2. Dyspnea (difficult or laboured breathing): 13 people, 29.55%
  3. Pericardial Effusion (fluid around the heart): 11 people, 25.00%
  4. Pericarditis (inflammation of the pericardium): 9 people, 20.45%
  5. Nausea (feeling of having an urge to vomit): 7 people, 15.91%
  6. Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 7 people, 15.91%
  7. Nausea And Vomiting: 7 people, 15.91%
  8. Fatigue (feeling of tiredness): 6 people, 13.64%
  9. Malignant Neoplasm Progression (cancer tumour came back): 6 people, 13.64%
  10. Neck Pain: 5 people, 11.36%

What are the existing conditions these people have? *

  1. Lung Cancer - Non-Small Cell (lung cancer): 12 people, 27.27%
  2. Lung Neoplasm Malignant (cancer tumour of lung): 9 people, 20.45%
  3. Non-Small Cell Lung Cancer Stage Iv: 4 people, 9.09%
  4. Lung Cancer Metastatic (lung cancer spreads to other parts): 2 people, 4.55%
  5. Lung Adenocarcinoma (a form of non-small cell lung cancer): 2 people, 4.55%
  6. Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 1 person, 2.27%
  7. Prostate Cancer: 1 person, 2.27%
  8. Non-Small Cell Lung Cancer Metastatic (type of epithelial lung cancer spreads to other parts): 1 person, 2.27%
  9. Lung Adenocarcinoma Stage Iv (the cancer has spread to other organs of the body, such as the other lung, brain, or liver): 1 person, 2.27%
  10. Lower Respiratory Tract Infection: 1 person, 2.27%

* Approximation only. Some reports may have incomplete information.

Do you take Zykadia and have Chest pain?

- Check whether Chest pain is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Zykadia:

Chest pain treatments and more:

How severe was Chest pain and when was it recovered:

Expand to all the drugs that have ingredients of ceritinib:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Zykadia:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Chest pain:

Browse all the conditions that are associated with Chest pain:

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on ceritinib (the active ingredients of Zykadia) and Zykadia (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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