Zykadia and Hypokalemia - a phase IV clinical study of FDA data

Summary:

Hypokalemia is reported as a side effect among people who take Zykadia (ceritinib), especially for people who are male, 60+ old, have been taking the drug for 1 - 6 months also take Decadron, and have Non-small cell lung cancer stage iv.

The phase IV clinical study analyzes which people have Hypokalemia when taking Zykadia. It is created by eHealthMe based on reports of 2,091 people who have side effects when taking Zykadia from the FDA, and is updated regularly.

What is Zykadia?

Zykadia has active ingredients of ceritinib. eHealthMe is studying from 2,091 Zykadia users. Check the latest studies of Zykadia.

What is Hypokalemia?

Hypokalemia (low potassium) is found to be associated with 2,087 drugs and 3,091 conditions by eHealthMe. Check the latest studies of Hypokalemia.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 30, 2026

2,091 people reported to have side effects when taking Zykadia.
Among them, 20 people (0.96%) have Hypokalemia.

Could Zykadia cause Hypokalemia?

Among these 20 people:

How long have people been on Zykadia when they have Hypokalemia? *

  • < 1 month: 30.77 %
  • 1 - 6 months: 61.54 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 7.69 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Hypokalemia when taking Zykadia? *

  • female: 50 %
  • male: 50 %

What is the age of people who have Hypokalemia when taking Zykadia? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 5.88 %
  • 50-59: 5.88 %
  • 60+: 88.24 %

What are other drugs people take besides Zykadia? *

  1. Decadron: 2 people, 10.00%
  2. Wellbutrin: 1 person, 5.00%
  3. Tudorza Pressair: 1 person, 5.00%
  4. Triamcinolone: 1 person, 5.00%
  5. Symbicort: 1 person, 5.00%
  6. Potassium: 1 person, 5.00%
  7. Plavix: 1 person, 5.00%
  8. Oxycontin: 1 person, 5.00%
  9. Methotrexate: 1 person, 5.00%
  10. Megace: 1 person, 5.00%

What are other side effects people have besides Hypokalemia? *

  1. Malignant Neoplasm Progression (cancer tumour came back): 9 people, 45.00%
  2. Nausea (feeling of having an urge to vomit): 8 people, 40.00%
  3. Diarrhea: 8 people, 40.00%
  4. Non-Small Cell Lung Cancer Stage Iv: 6 people, 30.00%
  5. Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 5 people, 25.00%
  6. Metastases To Liver (cancer spreads to liver): 4 people, 20.00%
  7. Nausea And Vomiting: 4 people, 20.00%
  8. Blood Alkaline Phosphatase Increased: 4 people, 20.00%
  9. Gamma-Glutamyltransferase Increased: 4 people, 20.00%
  10. Metastases To Central Nervous System (cancer spreads to central nervous system): 3 people, 15.00%

What are the existing conditions these people have? *

  1. Non-Small Cell Lung Cancer Stage Iv: 9 people, 45.00%
  2. Lung Cancer - Non-Small Cell (lung cancer): 7 people, 35.00%
  3. Lung Neoplasm Malignant (cancer tumour of lung): 3 people, 15.00%
  4. Metastases To Meninges (cancer spreads to meninges): 1 person, 5.00%
  5. Metastases To Bone (cancer spreads to bone): 1 person, 5.00%
  6. Lung Adenocarcinoma Metastatic (a form of non-small cell lung cancer spreads to other part): 1 person, 5.00%
  7. Liver Disorder (liver diseases): 1 person, 5.00%
  8. Hyponatremia (abnormally low level of sodium in the blood; associated with dehydration): 1 person, 5.00%
  9. High Blood Pressure: 1 person, 5.00%
  10. Diabetes: 1 person, 5.00%

* Approximation only. Some reports may have incomplete information.

Do you take Zykadia and have Hypokalemia?

- Check whether Hypokalemia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Zykadia:

Hypokalemia treatments and more:

How severe was Hypokalemia and when was it recovered:

Expand to all the drugs that have ingredients of ceritinib:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Zykadia:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hypokalemia:

Browse all the conditions that are associated with Hypokalemia:

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on ceritinib (the active ingredients of Zykadia) and Zykadia (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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