Zykadia and Pain exacerbated - a phase IV clinical study of FDA data

Summary:

Pain exacerbated is reported as a side effect among people who take Zykadia (ceritinib), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Calcium, and have Lung neoplasm malignant.

The phase IV clinical study analyzes which people have Pain exacerbated when taking Zykadia. It is created by eHealthMe based on reports of 2,091 people who have side effects when taking Zykadia from the FDA, and is updated regularly.

What is Zykadia?

Zykadia has active ingredients of ceritinib. eHealthMe is studying from 2,091 Zykadia users. Check the latest studies of Zykadia.

What is Pain exacerbated?

Pain exacerbated is found to be associated with 3,979 drugs and 3,032 conditions by eHealthMe. Check the latest studies of Pain exacerbated.



On Aug, 05, 2026

2,091 people reported to have side effects when taking Zykadia.
Among them, 29 people (1.39%) have Pain exacerbated.

Could Zykadia cause Pain exacerbated?

Among these 29 people:

How long have people been on Zykadia when they have Pain exacerbated? *

  • < 1 month: 33.33 %
  • 1 - 6 months: 33.33 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 33.33 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Pain exacerbated when taking Zykadia? *

  • female: 81.48 %
  • male: 18.52 %

What is the age of people who have Pain exacerbated when taking Zykadia? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 10.53 %
  • 40-49: 21.05 %
  • 50-59: 26.32 %
  • 60+: 42.11 %

What are other drugs people take besides Zykadia? *

  1. Calcium: 3 people, 10.34%
  2. Vitamin B12: 2 people, 6.90%
  3. Percocet: 2 people, 6.90%
  4. Pepcid: 2 people, 6.90%
  5. Lasix: 2 people, 6.90%
  6. Keppra: 2 people, 6.90%
  7. Imodium A-D: 2 people, 6.90%
  8. Aleve: 2 people, 6.90%
  9. Advil: 2 people, 6.90%
  10. Xalkori: 1 person, 3.45%

What are other side effects people have besides Pain exacerbated? *

  1. Nausea (feeling of having an urge to vomit): 14 people, 48.28%
  2. Diarrhea: 10 people, 34.48%
  3. Fatigue (feeling of tiredness): 9 people, 31.03%
  4. Malignant Neoplasm Progression (cancer tumour came back): 7 people, 24.14%
  5. Nausea And Vomiting: 5 people, 17.24%
  6. Lung Neoplasm Malignant (cancer tumour of lung): 5 people, 17.24%
  7. Metastases To Bone (cancer spreads to bone): 5 people, 17.24%
  8. Dyspnea (difficult or laboured breathing): 5 people, 17.24%
  9. Pleural Effusion (water on the lungs): 4 people, 13.79%
  10. Gastrointestinal Disorder (functional problems of gastrointestinal tract): 4 people, 13.79%

What are the existing conditions these people have? *

  1. Lung Neoplasm Malignant (cancer tumour of lung): 12 people, 41.38%
  2. Lung Cancer - Non-Small Cell (lung cancer): 9 people, 31.03%
  3. Arterial Insufficiency (lack of enough blood flow through the arteries): 3 people, 10.34%
  4. Lung Adenocarcinoma (a form of non-small cell lung cancer): 2 people, 6.90%
  5. Non-Small Cell Lung Cancer Metastatic (type of epithelial lung cancer spreads to other parts): 1 person, 3.45%
  6. Nervous System Disorder (a general class of medical conditions affecting the nervous system): 1 person, 3.45%
  7. Metastases To Lung (cancer spreads to lung): 1 person, 3.45%
  8. Mesothelioma (rare type of cancer that occurs in the thin layer of cells lining the body's internal organs, known as the mesothelium): 1 person, 3.45%
  9. Lung Carcinoma Cell Type Unspecified Recurrent (lung cancer reoccurrence): 1 person, 3.45%
  10. Bronchial Carcinoma (lung cancer): 1 person, 3.45%

* Approximation only. Some reports may have incomplete information.

Do you take Zykadia and have Pain exacerbated?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Zykadia:

Pain exacerbated treatments and more:

How severe was Pain exacerbated and when was it recovered:

Expand to all the drugs that have ingredients of ceritinib:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Zykadia:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Pain exacerbated:

Browse all the conditions that are associated with Pain exacerbated:


How the study uses the data?

The study uses data from the FDA. It is based on ceritinib (the active ingredients of Zykadia) and Zykadia (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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