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Zyloprim and Skin erosion - a phase IV clinical study of FDA data

Summary:

Skin erosion is reported as a side effect among people who take Zyloprim (allopurinol), especially for people who are female, 30-39 old, also take Arava, and have Rosacea.

The phase IV clinical study analyzes which people have Skin erosion when taking Zyloprim. It is created by eHealthMe based on reports of 5,556 people who have side effects when taking Zyloprim from the FDA, and is updated regularly.

What is Zyloprim?

Zyloprim has active ingredients of allopurinol. It is often used in gout. eHealthMe is studying from 5,638 Zyloprim users. Check the latest studies of Zyloprim.

What is Skin erosion?

Skin erosion (a discontinuity of the skin) is found to be associated with 360 drugs and 527 conditions by eHealthMe. Check the latest studies of Skin erosion.

On Jul, 15, 2026

5,556 people reported to have side effects when taking Zyloprim.
Among them, 14 people (0.25%) have Skin erosion.

Could Zyloprim cause Skin erosion?

Among these 14 people:

What is the gender of people who have Skin erosion when taking Zyloprim? *

  • female: 92.31 %
  • male: 7.69 %

What is the age of people who have Skin erosion when taking Zyloprim? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 92.31 %
  • 40-49: 0.0 %
  • 50-59: 0.0 %
  • 60+: 7.69 %

What are other drugs people take besides Zyloprim? *

  1. Singulair: 13 people, 92.86%
  2. Lyrica: 13 people, 92.86%
  3. Arava: 13 people, 92.86%
  4. Synthroid: 12 people, 85.71%
  5. Lipitor: 12 people, 85.71%
  6. Humira: 12 people, 85.71%
  7. Enbrel: 12 people, 85.71%
  8. Depo-Medrol: 9 people, 64.29%
  9. Vitamin D: 2 people, 14.29%
  10. Nexium: 2 people, 14.29%

What are other side effects people have besides Skin erosion? *

  1. Lymphoma (cancer that begins in immune system cells): 13 people, 92.86%
  2. Blood Creatinine Abnormal: 13 people, 92.86%
  3. Lymph Follicular Hypertrophy (an increase in the size of the lymph node follicles): 13 people, 92.86%
  4. Lipoma (a growth of fatty tissue that slowly develops just under your skin): 13 people, 92.86%
  5. White Blood Cell Count Decreased: 13 people, 92.86%
  6. Joint Pain: 13 people, 92.86%
  7. Joint Effusion (presence of extra fluid in joint covering): 13 people, 92.86%
  8. High Blood Pressure: 13 people, 92.86%
  9. Headache (pain in head): 13 people, 92.86%
  10. Arthritis (form of joint disorder that involves inflammation of one or more joints): 13 people, 92.86%

What are the existing conditions these people have? *

  1. Rosacea (a skin condition that causes facial redness): 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Zyloprim and have Skin erosion?

- Check whether Skin erosion is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Zyloprim:

Skin erosion treatments and more:

How severe was Skin erosion and when was it recovered:

Expand to all the drugs that have ingredients of allopurinol:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Zyloprim:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Skin erosion:

Browse all the conditions that are associated with Skin erosion:

How the study uses the data?

The study uses data from the FDA. It is based on allopurinol (the active ingredients of Zyloprim) and Zyloprim (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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