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Zyprexa and Hyperthyroidism - a phase IV clinical study of FDA data

Summary:

Hyperthyroidism is reported as a side effect among people who take Zyprexa (olanzapine), especially for people who are female, 60+ old, have been taking the drug for 6 - 12 months also take Clonazepam, and have Schizophrenia.

The phase IV clinical study analyzes which people have Hyperthyroidism when taking Zyprexa. It is created by eHealthMe based on reports of 63,412 people who have side effects when taking Zyprexa from the FDA, and is updated regularly.

What is Zyprexa?

Zyprexa has active ingredients of olanzapine. It is often used in bipolar disorder. eHealthMe is studying from 64,720 Zyprexa users. Check the latest studies of Zyprexa.

What is Hyperthyroidism?

Hyperthyroidism (over activity of the thyroid gland) is found to be associated with 1,032 drugs and 1,426 conditions by eHealthMe. Check the latest studies of Hyperthyroidism.

On Nov, 14, 2025

63,412 people reported to have side effects when taking Zyprexa.
Among them, 49 people (0.08%) have Hyperthyroidism.

Could Zyprexa cause Hyperthyroidism?

Among these 49 people:

How long have people been on Zyprexa when they have Hyperthyroidism? *

  • < 1 month: 20.0 %
  • 1 - 6 months: 6.67 %
  • 6 - 12 months: 33.33 %
  • 1 - 2 years: 6.67 %
  • 2 - 5 years: 13.33 %
  • 5 - 10 years: 6.67 %
  • 10+ years: 13.33 %

What is the gender of people who have Hyperthyroidism when taking Zyprexa? *

  • female: 65.31 %
  • male: 34.69 %

What is the age of people who have Hyperthyroidism when taking Zyprexa? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 9.76 %
  • 20-29: 9.76 %
  • 30-39: 17.07 %
  • 40-49: 24.39 %
  • 50-59: 12.2 %
  • 60+: 26.83 %

What are other drugs people take besides Zyprexa? *

  1. Clonazepam: 7 people, 14.29%
  2. Omeprazole: 6 people, 12.24%
  3. Paxil: 6 people, 12.24%
  4. Risperdal: 5 people, 10.20%
  5. Neurontin: 5 people, 10.20%
  6. Nexium: 4 people, 8.16%
  7. Lorazepam: 4 people, 8.16%
  8. Zoloft: 4 people, 8.16%
  9. Seroquel: 4 people, 8.16%
  10. Synthroid: 4 people, 8.16%

What are other side effects people have besides Hyperthyroidism? *

  1. Weight Increased: 14 people, 28.57%
  2. Diabetes: 11 people, 22.45%
  3. High Blood Pressure: 10 people, 20.41%
  4. Insomnia (sleeplessness): 9 people, 18.37%
  5. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 8 people, 16.33%
  6. Dyspnea (difficult or laboured breathing): 8 people, 16.33%
  7. Headache (pain in head): 8 people, 16.33%
  8. Arrhythmias (irregular heartbeat): 7 people, 14.29%
  9. Dehydration (dryness resulting from the removal of water): 7 people, 14.29%
  10. Fatigue (feeling of tiredness): 7 people, 14.29%

What are the existing conditions these people have? *

  1. Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 13 people, 26.53%
  2. Pain: 3 people, 6.12%
  3. Hallucinations (sensations that appear real but are created by your mind): 2 people, 4.08%
  4. Arthritis (form of joint disorder that involves inflammation of one or more joints): 2 people, 4.08%
  5. Schizophrenia, Paranoid Type (delusions and auditory hallucinations but relatively normal intellectual functioning and expression of affect): 2 people, 4.08%
  6. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 4.08%
  7. Diabetes: 2 people, 4.08%
  8. Colorectal Cancer Metastatic (cancer of colon and rectal spreads to other parts): 1 person, 2.04%
  9. Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 1 person, 2.04%
  10. Constipation: 1 person, 2.04%

* Approximation only. Some reports may have incomplete information.

Do you take Zyprexa and have Hyperthyroidism?

- Check whether Hyperthyroidism is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Zyprexa:

Hyperthyroidism treatments and more:

How severe was Hyperthyroidism and when was it recovered:

Expand to all the drugs that have ingredients of olanzapine:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Zyprexa:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hyperthyroidism:

Browse all the conditions that are associated with Hyperthyroidism:

Drugs similar to Zyprexa and Hyperthyroidism :

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on olanzapine (the active ingredients of Zyprexa) and Zyprexa (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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