Zyprexa and Ulcerative colitis - a phase IV clinical study of FDA data

Summary:

Ulcerative colitis is reported as a side effect among people who take Zyprexa (olanzapine), especially for people who are male, 30-39 old, have been taking the drug for 1 - 2 years also take Seroquel, and have Schizophrenia.

The phase IV clinical study analyzes which people have Ulcerative colitis when taking Zyprexa. It is created by eHealthMe based on reports of 63,412 people who have side effects when taking Zyprexa from the FDA, and is updated regularly.

What is Zyprexa?

Zyprexa has active ingredients of olanzapine. It is often used in bipolar disorder. eHealthMe is studying from 64,722 Zyprexa users. Check the latest studies of Zyprexa.

What is Ulcerative colitis?

Ulcerative colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine) is found to be associated with 1,208 drugs and 2,040 conditions by eHealthMe. Check the latest studies of Ulcerative colitis.



On Apr, 18, 2026

63,412 people reported to have side effects when taking Zyprexa.
Among them, 41 people (0.06%) have Ulcerative colitis.

Could Zyprexa cause Ulcerative colitis?

Among these 41 people:

How long have people been on Zyprexa when they have Ulcerative colitis? *

  • < 1 month: 33.33 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 66.67 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Ulcerative colitis when taking Zyprexa? *

  • female: 38.46 %
  • male: 61.54 %

What is the age of people who have Ulcerative colitis when taking Zyprexa? *

  • 0-1: 2.78 %
  • 2-9: 0.0 %
  • 10-19: 5.56 %
  • 20-29: 16.67 %
  • 30-39: 27.78 %
  • 40-49: 11.11 %
  • 50-59: 25.0 %
  • 60+: 11.11 %

What are other drugs people take besides Zyprexa? *

  1. Seroquel: 12 people, 29.27%
  2. Depakote: 9 people, 21.95%
  3. Nexium: 8 people, 19.51%
  4. Wellbutrin: 7 people, 17.07%
  5. Effexor: 7 people, 17.07%
  6. Neurontin: 7 people, 17.07%
  7. Prednisone: 7 people, 17.07%
  8. Accutane: 6 people, 14.63%
  9. Asacol: 5 people, 12.20%
  10. Celexa: 5 people, 12.20%

What are other side effects people have besides Ulcerative colitis? *

  1. Weight Increased: 14 people, 34.15%
  2. Insomnia (sleeplessness): 8 people, 19.51%
  3. Gastrointestinal Haemorrhage (bleeding gastrointestinal tract): 8 people, 19.51%
  4. Abdominal Pain: 7 people, 17.07%
  5. Constipation: 7 people, 17.07%
  6. Irritable Bowel Syndrome: 6 people, 14.63%
  7. Nerve Injury: 6 people, 14.63%
  8. Inflammation: 6 people, 14.63%
  9. Suicidal Ideation: 6 people, 14.63%
  10. Anaemia (lack of blood): 5 people, 12.20%

What are the existing conditions these people have? *

  1. Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 11 people, 26.83%
  2. Sleep Disorder: 5 people, 12.20%
  3. Acne (skin problems that cause pimples): 4 people, 9.76%
  4. Psychotic Disorder: 4 people, 9.76%
  5. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 7.32%
  6. Pain: 3 people, 7.32%
  7. Migraine (headache): 3 people, 7.32%
  8. Acne Cystic (skin problems that cause pimples): 2 people, 4.88%
  9. Agitation (state of anxiety or nervous excitement): 2 people, 4.88%
  10. Weight Decreased: 1 person, 2.44%

* Approximation only. Some reports may have incomplete information.

Do you take Zyprexa and have Ulcerative colitis?

- Check whether Ulcerative colitis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Zyprexa:

Ulcerative colitis treatments and more:

How severe was Ulcerative colitis and when was it recovered:

Expand to all the drugs that have ingredients of olanzapine:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Zyprexa:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Ulcerative colitis:

Browse all the conditions that are associated with Ulcerative colitis:

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on olanzapine (the active ingredients of Zyprexa) and Zyprexa (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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