Zyrtec and Exomphalos - a phase IV clinical study of FDA data

Summary:

Exomphalos is reported as a side effect among people who take Zyrtec (cetirizine hydrochloride), especially for people who are male, 30-39 old, also take Keppra, and have Convulsion.

The phase IV clinical study analyzes which people have Exomphalos when taking Zyrtec. It is created by eHealthMe based on reports of 109,528 people who have side effects when taking Zyrtec from the FDA, and is updated regularly.

What is Zyrtec?

Zyrtec has active ingredients of cetirizine hydrochloride. It is often used in allergies. eHealthMe is studying from 114,619 Zyrtec users. Check the latest studies of Zyrtec.

What is Exomphalos?

Exomphalos (weakness of the baby's abdominal wall where the umbilical cord joins it) is found to be associated with 90 drugs and 133 conditions by eHealthMe. Check the latest studies of Exomphalos.

On Jul, 13, 2026

109,528 people reported to have side effects when taking Zyrtec.
Among them, 14 people (0.01%) have Exomphalos.

Among these 14 people:

What is the gender of people who have Exomphalos when taking Zyrtec? *

female: 7.69 %
male: 92.31 %

What is the age of people who have Exomphalos when taking Zyrtec? *

What are other drugs people take besides Zyrtec? *

Keppra: 12 people, 85.71%
Lamictal: 8 people, 57.14%
Lamotrigine: 3 people, 21.43%
Diclofenac: 2 people, 14.29%
Lamictal Cd: 1 person, 7.14%

What are other side effects people have besides Exomphalos? *

Maternal Exposure During Pregnancy (use of substance during pregnancy): 2 people, 14.29%
Hydrops Foetalis (fetus characterized by an accumulation of fluid): 2 people, 14.29%
Foetal Exposure During Pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect): 2 people, 14.29%
Drug Exposure During Pregnancy: 2 people, 14.29%

What are the existing conditions these people have? *

Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 9 people, 64.29%
Hypersensitivity: 4 people, 28.57%
Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Zyrtec and have Exomphalos?

- Check whether Exomphalos is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Zyrtec:

Zyrtec (114,619 reports)

Exomphalos treatments and more:

Exomphalos (1,001 reports)

Browse all side effects of Zyrtec:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Exomphalos:

Exomphalos (90 drugs)

Browse all the conditions that are associated with Exomphalos:

Exomphalos (133 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on cetirizine hydrochloride (the active ingredients of Zyrtec) and Zyrtec (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.