Zyrtec and Sinus disorder - a phase IV clinical study of FDA data

Summary:

Sinus disorder is reported as a side effect among people who take Zyrtec (cetirizine hydrochloride), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Singulair, and have Immunodeficiency common variable.

The phase IV clinical study analyzes which people have Sinus disorder when taking Zyrtec. It is created by eHealthMe based on reports of 109,528 people who have side effects when taking Zyrtec from the FDA, and is updated regularly.

What is Zyrtec?

Zyrtec has active ingredients of cetirizine hydrochloride. It is often used in allergies. eHealthMe is studying from 114,619 Zyrtec users. Check the latest studies of Zyrtec.

What is Sinus disorder?

Sinus disorder (disease of sinus) is found to be associated with 1,254 drugs and 1,076 conditions by eHealthMe. Check the latest studies of Sinus disorder.

On Jul, 07, 2026

109,528 people reported to have side effects when taking Zyrtec.
Among them, 612 people (0.56%) have Sinus disorder.

Among these 612 people:

* Approximation only. Some reports may have incomplete information.

Do you take Zyrtec and have Sinus disorder?

- Check whether Sinus disorder is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Zyrtec:

Zyrtec (114,619 reports)

Sinus disorder treatments and more:

Sinus disorder (30,270 reports)

How severe was Sinus disorder and when was it recovered:

Sinus disorder in Zyrtec

Expand to all the drugs that have ingredients of cetirizine hydrochloride:

Sinus disorder and drugs with ingredients of cetirizine hydrochloride (1,000 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Zyrtec:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Sinus disorder:

Sinus disorder (1,254 drugs)

Browse all the conditions that are associated with Sinus disorder:

Sinus disorder (1,076 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on cetirizine hydrochloride (the active ingredients of Zyrtec) and Zyrtec (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.