Zyrtec and Vitiligo - a phase IV clinical study of FDA data

Summary:

Vitiligo is reported as a side effect among people who take Zyrtec (cetirizine hydrochloride), especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months also take Prednisone, and have Immunodeficiency.

The phase IV clinical study analyzes which people have Vitiligo when taking Zyrtec. It is created by eHealthMe based on reports of 109,528 people who have side effects when taking Zyrtec from the FDA, and is updated regularly.

What is Zyrtec?

Zyrtec has active ingredients of cetirizine hydrochloride. It is often used in allergies. eHealthMe is studying from 114,620 Zyrtec users. Check the latest studies of Zyrtec.

What is Vitiligo?

Vitiligo (pigment is lost from areas of the skin) is found to be associated with 167 drugs and 307 conditions by eHealthMe. Check the latest studies of Vitiligo.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 18, 2026

109,528 people reported to have side effects when taking Zyrtec.
Among them, 12 people (0.01%) have Vitiligo.

Among these 12 people:

How long have people been on Zyrtec when they have Vitiligo? *

What is the gender of people who have Vitiligo when taking Zyrtec? *

female: 83.33 %
male: 16.67 %

What is the age of people who have Vitiligo when taking Zyrtec? *

What are other drugs people take besides Zyrtec? *

Prednisone: 4 people, 33.33%
Medrol: 3 people, 25.00%
Vitamin D3: 3 people, 25.00%
Singulair: 3 people, 25.00%
Memantine: 2 people, 16.67%
Arginine: 2 people, 16.67%
Fluticasone Propionate: 2 people, 16.67%
Epinephrine: 2 people, 16.67%
Diphenhydramine Hydrochloride: 2 people, 16.67%
Colloidal Silver: 2 people, 16.67%

What are other side effects people have besides Vitiligo? *

Sinusitis (inflammation of sinus): 3 people, 25.00%
Urinary Tract Infection: 3 people, 25.00%
Upper Respiratory Tract Infection: 3 people, 25.00%
Viral Infection: 3 people, 25.00%
Vision Blurred: 2 people, 16.67%
Fall: 2 people, 16.67%
Peripheral Swelling: 2 people, 16.67%
Influenza Like Illness: 2 people, 16.67%
Dermatitis Contact (skin reaction (dermatitis) resulting from exposure to allergens): 2 people, 16.67%
Drug Hypersensitivity: 2 people, 16.67%

What are the existing conditions these people have? *

Immunodeficiency Common Variable: 2 people, 16.67%
Rashes (redness): 2 people, 16.67%
Psoriasis (immune-mediated disease that affects the skin): 2 people, 16.67%
Pain: 2 people, 16.67%
Immunodeficiency: 2 people, 16.67%
Upper Respiratory Tract Infection: 1 person, 8.33%
Asthma: 1 person, 8.33%
Bone Lesion (bone with abnormalities. bone lesions can result from growth formations, infections, or injuries): 1 person, 8.33%
Depression: 1 person, 8.33%
Dermatitis Atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder): 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Zyrtec and have Vitiligo?

- Check whether Vitiligo is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Zyrtec:

Zyrtec (114,620 reports)

Vitiligo treatments and more:

Vitiligo (3,513 reports)

Browse all side effects of Zyrtec:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Vitiligo:

Vitiligo (167 drugs)

Browse all the conditions that are associated with Vitiligo:

Vitiligo (307 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on cetirizine hydrochloride (the active ingredients of Zyrtec) and Zyrtec (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.