Sciatica in Amlodipine - how severe and when it was recovered? (a real world drug study)

Summary:

We study how severe was Sciatica, when it was recovered, drug effectiveness, race, and more among people who take Amlodipine (amlodipine besylate). This phase IV clinical study is created by eHealthMe based on reports submitted to eHealthMe, and is updated regularly.

What is Amlodipine?

Amlodipine has active ingredients of amlodipine besylate. It is often used in high blood pressure. eHealthMe is studying from 354,830 Amlodipine users. Check the latest studies of Amlodipine.

What is Sciatica?

Sciatica (a set of symptoms including pain caused by general compression or irritation of one of five spinal nerve roots of each sciatic nerve) is found to be associated with 1,137 drugs and 1,436 conditions by eHealthMe. Check the latest studies of Sciatica.



On Aug, 11, 2026

21 people who have Sciatica while taking Amlodipine were studied.

Could Amlodipine cause Sciatica?

Severity of Sciatica *:

  • least: 5 %
  • moderate: 35 %
  • severe: 50 %
  • most severe: 10 %

When people recovered from Sciatica *:

  • while on drug: 8.33 %
  • after off the drug: 16.67 %
  • not yet: 75.0 %

Effectiveness of Amlodipine *:

  • not at all: 0.0 %
  • somewhat: 20.0 %
  • moderate: 26.67 %
  • high: 40.0 %
  • very high: 13.33 %

Race of the people *:

  • African American, Non-Hispanic: 35.29 %
  • American Indian/Alaska Native: 0.0 %
  • Asian: 0.0 %
  • Hispanic: 0.0 %
  • Native Hawaiians/Pacific Islanders: 0.0 %
  • Two or more races: 0.0 %
  • White, Non-Hispanic: 64.71 %

Time on Amlodipine *:

  • < 1 month: 0.0 %
  • 1 - 6 months: 11.76 %
  • 6 - 12 months: 5.88 %
  • 1 - 2 years: 11.76 %
  • 2 - 5 years: 35.29 %
  • 5 - 10 years: 11.76 %
  • 10+ years: 23.53 %

Gender of people when taking Amlodipine *:

  • female: 61.9 %
  • male: 38.1 %

Age of people when taking Amlodipine *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 4.76 %
  • 40-49: 19.05 %
  • 50-59: 28.57 %
  • 60+: 47.62 %

Conditions people have *:

  1. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 6 people, 28.57%
  2. High Blood Cholesterol: 3 people, 14.29%
  3. Depression: 2 people, 9.52%
  4. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 9.52%
  5. Allergies: 2 people, 9.52%
  6. Arthritis (form of joint disorder that involves inflammation of one or more joints): 2 people, 9.52%
  7. Stress And Anxiety: 2 people, 9.52%
  8. Cholesterosis (abnormal deposition of cholesterol in tissues): 2 people, 9.52%
  9. Diabetes: 2 people, 9.52%
  10. Muscle Spasms (muscle contraction): 2 people, 9.52%

Other drugs people take besides Amlodipine *:

  1. Synthroid: 4 people, 19.05%
  2. Metformin: 3 people, 14.29%
  3. Levothyroxine Thyroid: 2 people, 9.52%
  4. Losartan: 2 people, 9.52%
  5. Clonidine: 2 people, 9.52%
  6. Cetirizine Hydrochloride: 2 people, 9.52%
  7. Tizanidine Hydrochloride: 2 people, 9.52%
  8. Gabapentin: 2 people, 9.52%
  9. Allopurinol: 2 people, 9.52%
  10. Vitamin D: 2 people, 9.52%

Other side effects people have besides Sciatica *:

  1. Headache (pain in head): 2 people, 9.52%
  2. Arthritis (form of joint disorder that involves inflammation of one or more joints): 2 people, 9.52%
  3. Neck Pain: 2 people, 9.52%
  4. Vulval Lichen Sclerosis Et Atrophicus (degeneration and shrinkage of the skin of the vagina and vulva): 1 person, 4.76%
  5. Depression: 1 person, 4.76%
  6. High Blood Cholesterol: 1 person, 4.76%
  7. Heavy Or Prolong Menstrual Bleeding: 1 person, 4.76%
  8. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 4.76%
  9. Foot, Leg, And Ankle Swelling: 1 person, 4.76%
  10. Excessive Or Unwanted Hair In Women: 1 person, 4.76%

* Approximation only. Some reports may have incomplete information.

Do you take Amlodipine and have Sciatica?

Check whether Sciatica is associated with a drug or a condition

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Related studies

How the study uses the data?

The study is based on amlodipine besylate (the active ingredients of Amlodipine). Other drugs that have the same active ingredients (e.g. generic drugs) are considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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