Muscle twitching in Spironolactone - how severe and when it was recovered? (a real world drug study)

Summary:

We study how severe was Muscle twitching, when it was recovered, drug effectiveness, race, and more among people who take Spironolactone (spironolactone). This phase IV clinical study is created by eHealthMe based on reports submitted to eHealthMe, and is updated regularly.

What is Spironolactone?

Spironolactone has active ingredients of spironolactone. It is often used in acne. eHealthMe is studying from 122,947 Spironolactone users. Check the latest studies of Spironolactone.

What is Muscle twitching?

Muscle twitching is found to be associated with 1,240 drugs and 1,905 conditions by eHealthMe. Check the latest studies of Muscle twitching.

On Jun, 09, 2026

14 people who have Muscle twitching while taking Spironolactone were studied.

Could Spironolactone cause Muscle twitching?

Severity of Muscle twitching *:

least: 15.38 %
moderate: 53.85 %
severe: 23.08 %
most severe: 7.69 %

When people recovered from Muscle twitching *:

while on drug: 0.0 %
after off the drug: 11.11 %
not yet: 88.89 %

Effectiveness of Spironolactone *:

not at all: 9.09 %
somewhat: 27.27 %
moderate: 27.27 %
high: 27.27 %
very high: 9.09 %

Race of the people *:

African American, Non-Hispanic: 0.0 %
American Indian/Alaska Native: 0.0 %
Asian: 0.0 %
Hispanic: 0.0 %
Native Hawaiians/Pacific Islanders: 0.0 %
Two or more races: 0.0 %
White, Non-Hispanic: 100 %

Time on Spironolactone *:

Gender of people when taking Spironolactone *:

female: 85.71 %
male: 14.29 %

Age of people when taking Spironolactone *:

Conditions people have *:

High Blood Cholesterol: 2 people, 14.29%
Allergies: 2 people, 14.29%
Fluid Retention (an abnormal accumulation of fluid in the blood): 2 people, 14.29%
Stress And Anxiety: 2 people, 14.29%
Attention Deficit Hyperactivity Disorder (a chronic condition including attention difficulty, hyperactivity, and impulsiveness): 2 people, 14.29%
Insomnia (sleeplessness): 2 people, 14.29%
Peripheral Neuropathy (damage to nerves of the peripheral nervous system): 2 people, 14.29%
Migraine (headache): 2 people, 14.29%
Diabetes Mellitus Inadequate Control: 1 person, 7.14%
Foot, Leg, And Ankle Swelling: 1 person, 7.14%

Other drugs people take besides Spironolactone *:

Other side effects people have besides Muscle twitching *:

Weakness: 2 people, 14.29%
Abdominal Pain: 2 people, 14.29%
Dizziness: 2 people, 14.29%
Fatigue (feeling of tiredness): 2 people, 14.29%
Itching: 1 person, 7.14%
Dizziness Aggravated: 1 person, 7.14%
Dry Mouth: 1 person, 7.14%
Gastroparesis (delayed emptying of food from the stomach): 1 person, 7.14%
Headache (pain in head): 1 person, 7.14%
Hip Pain: 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Spironolactone and have Muscle twitching?

Check whether Muscle twitching is associated with a drug or a condition

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Related studies

Muscle twitching in Spironolactone

How the study uses the data?

The study is based on spironolactone (the active ingredients of Spironolactone). Other drugs that have the same active ingredients (e.g. generic drugs) are considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.