Benzonatate vs. Keflex: side effect and effectiveness comparison (a real world drug study)
Summary:
We compare the side effects and drug effectiveness of Benzonatate and Keflex. The phase IV clinical study is created by eHealthMe based on reports (from sources including the FDA) of 67,585 people who take Benzonatate and Keflex, and is updated regularly.
What is Benzonatate?
Benzonatate has active ingredients of benzonatate. It is often used in cough. eHealthMe is studying from 17,274 Benzonatate users. Check the latest studies of Benzonatate.
What is Keflex?
Keflex has active ingredients of cephalexin. It is often used in infection. eHealthMe is studying from 15,844 Keflex users. Check the latest studies of Keflex.
67,585 people who take Benzonatate and Keflex are studied.

Drugs being compared in this study:
- Benzonatate (benzonatate)
- Keflex (cephalexin)
Most common side effects of the drugs, overall:
Most common side effects of the drugs, in long term (1+ years) use:
Drug effectiveness:
Benzonatate:
- not at all: 7.35 %
- somewhat: 37.94 %
- moderate: 30.29 %
- high: 16.76 %
- very high: 7.65 %
Keflex:
- not at all: 7.68 %
- somewhat: 24.53 %
- moderate: 32.74 %
- high: 26.21 %
- very high: 8.84 %
Want to compare Benzonatate with Keflex?
- Personalize this study to your gender and age (0-99+)How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Related publications that referenced our studies
- Agrawal A, Rao M, Jasdanwala S, Mathur A, Eng M, "Cephalexin Induced Cholestatic Jaundice", Case reports in gastrointestinal medicine, 2014 Aug .
- Agrawal A, Rao M, Jasdanwala S, Mathur A, Eng M, "Cephalexin Induced Cholestatic Jaundice", Case reports in gastrointestinal medicine, 2014 Aug .
Related studies
Alternative drugs to, pros and cons of:
- Benzonatate (16,668 reports)
- Keflex (14,913 reports)
Browse all side effects of Benzonatate:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Keflex:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study is based on benzonatate and cephalexin (the active ingredients of Benzonatate and Keflex, respectively). Other drugs that have the same active ingredients (e.g. generic drugs or brand names) are also considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
Recent studies on eHealthMe:
- Drug interactions of Doxazosin Mesylate and Zolpidem - 3 seconds ago
- Could Clinoril cause Blood Creatinine Increased? - 9 seconds ago
- Could Acetylsalicylic Acid cause Viith Nerve Paralysis? - 14 seconds ago
- Could Tiazac cause Oropharyngeal Pain? - 16 seconds ago
- Drug interactions of Fentora and Xartemis Xr - 28 seconds ago
- Primatene Mist vs. Flovent, side effect and effectiveness comparison - 42 seconds ago
- Could Benzonatate cause Visual Impairment? - 48 seconds ago
- Could Glucophage cause Biliary Dilatation? - 59 seconds ago
- Could Aspirin cause Sciatica? - a minute ago
- Could Pletal cause Abdominal Pain? - a minute ago