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Abilify vs. Nardil: side effect and effectiveness comparison (a real world drug study)

Summary:

We compare the side effects and drug effectiveness of Abilify and Nardil. The phase IV clinical study is created by eHealthMe based on reports (from sources including the FDA) of 139,263 people who take Abilify and Nardil, and is updated regularly.

What is Abilify?

Abilify has active ingredients of aripiprazole. It is often used in depression. eHealthMe is studying from 101,441 Abilify users. Check the latest studies of Abilify.

What is Nardil?

Nardil has active ingredients of phenelzine sulfate. It is often used in depression. eHealthMe is studying from 2,327 Nardil users. Check the latest studies of Nardil.

On Oct, 17, 2025

139,263 people who take Abilify and Nardil are studied.

Abilify vs Nardil drug comparison reports.

Drugs being compared in this study:

  • Nardil (phenelzine sulfate)
  • Abilify (aripiprazole)

Most common side effects of the drugs, overall:

Abilify:

  1. Drug Ineffective
  2. Weight Increased
  3. Anxiety
  4. Fatigue (feeling of tiredness)
  5. Suicidal Ideation
  6. Nausea (feeling of having an urge to vomit)
  7. Suicide Attempt
  8. Insomnia (sleeplessness)
  9. Tremor (trembling or shaking movements in one or more parts of your body)
  10. Headache (pain in head)

Nardil:

  1. Drug Ineffective
  2. Anxiety
  3. Headache (pain in head)
  4. Weight Increased
  5. Insomnia (sleeplessness)
  6. Fatigue (feeling of tiredness)
  7. Dizziness
  8. Nausea (feeling of having an urge to vomit)
  9. Fall
  10. Malaise (a feeling of general discomfort or uneasiness)

Most common side effects of the drugs, in long term (1+ years) use:

Abilify:

  1. Obsessive-Compulsive Disorder (an anxiety disorder characterized by intrusive thoughts that produce uneasiness, apprehension, fear, or worry;)
  2. Injury
  3. Emotional Distress
  4. Mental Disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
  5. Anxiety
  6. Compulsive Shopping
  7. Suicidal Ideation
  8. Suicide Attempt
  9. Pain
  10. Weight Increased

Nardil:

  1. Anxiety
  2. Drug Ineffective
  3. Fatigue (feeling of tiredness)
  4. Hypertensive Crisis
  5. Agitation (state of anxiety or nervous excitement)
  6. Haemorrhage Intracranial (bleeding within the skull)
  7. Weight Decreased
  8. Dizziness
  9. Asthenia (weakness)
  10. Panic Attack

Drug effectiveness:

Abilify:

  • not at all: 8.66 %
  • somewhat: 23.9 %
  • moderate: 28.7 %
  • high: 25.99 %
  • very high: 12.74 %

Nardil:

  • not at all: 3.85 %
  • somewhat: 17.69 %
  • moderate: 27.69 %
  • high: 35.38 %
  • very high: 15.38 %

Want to compare Abilify with Nardil?

Personalize this study to your gender and age (0-99+).

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Related publications that referenced our studies

Related studies

Alternative drugs to, pros and cons of:

Common Abilify side effects:

Browse all side effects of Abilify:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common Nardil side effects:

Browse all side effects of Nardil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study is based on aripiprazole and phenelzine sulfate (the active ingredients of Abilify and Nardil, respectively). Other drugs that have the same active ingredients (e.g. generic drugs or brand names) are also considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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