Nolvadex vs. Neulasta: side effect and effectiveness comparison - a phase IV clinical study
Summary:
We compare the side effects and drug effectiveness of Nolvadex and Neulasta. The phase IV clinical study is created by eHealthMe based on reports (from sources including the FDA) of 119,316 people who take Nolvadex and Neulasta, and is updated regularly. You can use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
119,316 people who take Nolvadex and Neulasta are studied.
What is Nolvadex?
Nolvadex has active ingredients of tamoxifen citrate. It is often used in breast cancer. eHealthMe is studying from 5,417 Nolvadex users for its effectiveness, alternative drugs and more.
What is Neulasta?
Neulasta has active ingredients of pegfilgrastim. It is often used in agranulocytosis. eHealthMe is studying from 79,300 Neulasta users for its effectiveness, alternative drugs and more.
Number of reports submitted per year:

Drugs being compared in this study:
- Neulasta (pegfilgrastim)
- Nolvadex (tamoxifen citrate)
Most common side effects of the drugs, overall:
Most common side effects of the drugs, in long term (1+ years) use:
Drug effectiveness:
Nolvadex:
- not at all: 2.27 %
- somewhat: 13.38 %
- moderate: 26.77 %
- high: 34.85 %
- very high: 22.73 %
Neulasta:
- not at all: 12.5 %
- somewhat: 7.14 %
- moderate: 19.64 %
- high: 32.14 %
- very high: 28.57 %
Want to compare Nolvadex with Neulasta?
Personalize this study to your gender and age (0-99+).How to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related publications that referenced our studies
- Khan A, Yasin Z, "Hyperleukocytosis Caused By Neulasta Complicated By Leukostasis Versus Asymptomatic Uncomplicated Hyperleukocytosis In AML. Two Cases and When To Leukapherese.", Am Soc Hematology, 2017 Jan .
- K?rm?z?bekmez H, Yesiltepe Mutlu RG, Dursun F, ??güven ?P, "Tamoxifen-associated hirsutism: an unusual side effect in a 5-year-old girl with McCune-Albright syndrome", Journal of Pediatric Endocrinology and Metabolism, 2015 Sep .
Related studies
Alternative drugs to, pros and cons of:
Common Nolvadex side effects:
- Death: 606 reports
- Hot flush (sudden feelings of heat): 267 reports
- Fatigue (feeling of tiredness): 200 reports
- Pain: 188 reports
- Fever: 174 reports
Browse all side effects of Nolvadex:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Neulasta side effects:
- Death: 2,369 reports
- Fatigue (feeling of tiredness): 2,306 reports
- Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 2,065 reports
- Fever: 2,051 reports
- Pain: 2,007 reports
Browse all side effects of Neulasta:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study is based on tamoxifen citrate and pegfilgrastim (the active ingredients of Nolvadex and Neulasta, respectively). Other drugs that have the same active ingredients (e.g. generic drugs or brand names) are also considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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