Paroxetine vs. Valium: side effect and effectiveness comparison (a real world drug study)
Summary:
We compare the side effects and drug effectiveness of Paroxetine and Valium. The phase IV clinical study is created by eHealthMe based on reports (from sources including the FDA) of 304,626 people who take Paroxetine and Valium, and is updated regularly.
What is Paroxetine?
Paroxetine has active ingredients of paroxetine hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 65,088 Paroxetine users. Check the latest studies of Paroxetine.
What is Valium?
Valium has active ingredients of diazepam. It is often used in stress and anxiety. eHealthMe is studying from 48,647 Valium users. Check the latest studies of Valium.
304,626 people who take Paroxetine and Valium are studied.

Drugs being compared in this study:
- Paroxetine (paroxetine hydrochloride)
- Valium (diazepam)
Most common side effects of the drugs, overall:
Most common side effects of the drugs, in long term (1+ years) use:
Drug effectiveness:
Paroxetine:
- not at all: 4.38 %
- somewhat: 19.43 %
- moderate: 33.04 %
- high: 31.72 %
- very high: 11.43 %
Valium:
- not at all: 3.32 %
- somewhat: 21.66 %
- moderate: 34.58 %
- high: 27.47 %
- very high: 12.98 %
Want to compare Paroxetine with Valium?
- Personalize this study to your gender and age (0-99+)How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Related publications that referenced our studies
- Coskun M, Adak I, Akaltun I, "Bilateral gynecomastia in a preadolescent boy while under treatment with methylphenidate and paroxetine", Journal of clinical psychopharmacology, 2014 Aug .
- Coskun M, Adak I, Akaltun I, "Bilateral gynecomastia in a preadolescent boy while under treatment with methylphenidate and paroxetine", Journal of clinical psychopharmacology, 2014 Aug .
Related studies
Alternative drugs to, pros and cons of:
- Paroxetine (63,809 reports)
- Valium (45,675 reports)
Browse all side effects of Paroxetine:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Valium:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study is based on paroxetine hydrochloride and diazepam (the active ingredients of Paroxetine and Valium, respectively). Other drugs that have the same active ingredients (e.g. generic drugs or brand names) are also considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
Recent studies on eHealthMe:
- Could Abilify cause Sudden Onset Of Sleep? - 5 seconds ago
- Hydrocodone and Light-Headedness When Standing Up for Women aged 40-49 - 12 seconds ago
- Hydrocodone and Lightheadedness for Women aged 40-49 - 13 seconds ago
- Hydrocodone and Vertigo for Women aged 40-49 - 13 seconds ago
- Hydrocodone and Loss Of Balance for Women aged 40-49 - 13 seconds ago
- Hydrocodone and Lightheadedness - Dizzy for Women aged 40-49 - 13 seconds ago
- Hydrocodone and Dizziness for Women aged 40-49 - 14 seconds ago
- Drug interactions of Valtrex and Omega-3 - 20 seconds ago
- Could Nasacort cause Abdominal Pain Upper? - 22 seconds ago
- Neoplasm Prostate and drugs of ingredients of zoledronic acid - 25 seconds ago