Paxil vs. Ibuprofen and diphenhydramine citrate: side effect and effectiveness comparison (a real world drug study)

Summary:

We compare the side effects and drug effectiveness of Paxil and Ibuprofen and diphenhydramine citrate. The phase IV clinical study is created by eHealthMe based on reports (from sources including the FDA) of 157,497 people who take Paxil and Ibuprofen and diphenhydramine citrate, and is updated regularly.

What is Paxil?

Paxil has active ingredients of paroxetine hydrochloride. It is often used in depression. eHealthMe is studying from 92,547 Paxil users. Check the latest studies of Paxil.

What is Ibuprofen and diphenhydramine citrate?

Ibuprofen and diphenhydramine citrate has active ingredients of diphenhydramine citrate; ibuprofen. It is often used in insomnia. eHealthMe is studying from 318 Ibuprofen and diphenhydramine citrate users. Check the latest studies of Ibuprofen and diphenhydramine citrate.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Sep, 01, 2026

157,497 people who take Paxil and Ibuprofen and diphenhydramine citrate are studied.

Paxil vs Ibuprofen and diphenhydramine citrate drug comparison reports.

Drugs being compared in this study:

  • Paxil (paroxetine hydrochloride)
  • Ibuprofen And Diphenhydramine Citrate (diphenhydramine citrate; ibuprofen)

Most common side effects of the drugs, overall:

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Most common side effects of the drugs, in long term (1+ years) use:

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Drug effectiveness:

Paxil:

  • not at all: 5.5 %
  • somewhat: 18.53 %
  • moderate: 33.25 %
  • high: 31.56 %
  • very high: 11.17 %

Ibuprofen And Diphenhydramine Citrate:

  • not at all: 0 %
  • somewhat: 6.25 %
  • moderate: 43.75 %
  • high: 31.25 %
  • very high: 18.75 %

Want to compare Paxil with Ibuprofen and diphenhydramine citrate?

- Personalize this study to your gender and age (0-99+)

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.



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Browse all side effects of Paxil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Ibuprofen and diphenhydramine citrate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study is based on paroxetine hydrochloride and diphenhydramine citrate; ibuprofen (the active ingredients of Paxil and Ibuprofen and diphenhydramine citrate, respectively). Other drugs that have the same active ingredients (e.g. generic drugs or brand names) are also considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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