Simcor vs. Carvedilol: side effect and effectiveness comparison - a phase IV clinical study
Summary:
We compare the side effects and drug effectiveness of Simcor and Carvedilol. The phase IV clinical study is created by eHealthMe based on reports (from sources including the FDA) of 153,406 people who take Simcor and Carvedilol, and is updated regularly. You can use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
153,406 people who take Simcor and Carvedilol are studied.
What is Simcor?
Simcor has active ingredients of niacin; simvastatin. It is often used in high blood cholesterol. eHealthMe is studying from 11,600 Simcor users for its effectiveness, alternative drugs and more.
What is Carvedilol?
Carvedilol has active ingredients of carvedilol. It is often used in high blood pressure. eHealthMe is studying from 97,371 Carvedilol users for its effectiveness, alternative drugs and more.
Number of reports submitted per year:

Drugs being compared in this study:
- Simcor (niacin; simvastatin)
- Carvedilol (carvedilol)
Most common side effects of the drugs, overall:
Most common side effects of the drugs, in long term (1+ years) use:
Drug effectiveness:
Simcor:
- not at all: 2.86 %
- somewhat: 17.14 %
- moderate: 38.57 %
- high: 32.86 %
- very high: 8.57 %
Carvedilol:
- not at all: 2.25 %
- somewhat: 15.59 %
- moderate: 35.12 %
- high: 36.04 %
- very high: 10.99 %
Want to compare Simcor with Carvedilol?
Personalize this study to your gender and age (0-99+).How to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related publications that referenced our studies
- Barold, S. S., & Upton, S. , "Hyperkalemia Induced by the Sequential Administration of Metoprolol and Carvedilol", Case reports in cardiology, 2018 Jan .
- Kim MS, Baek IH, "Effect of dronedarone on the pharmacokinetics of carvedilol following oral administration to rats", European Journal of Pharmaceutical Sciences, 2018 Jan .
Related studies
Alternative drugs to, pros and cons of:
- Simcor (11,435 reports)
- Carvedilol (95,227 reports)
Common Simcor side effects:
- Skin blushing/flushing (a sudden reddening of the face, neck): 5,358 reports
- Itching: 2,068 reports
- Rashes (redness): 1,284 reports
- Headache (pain in head): 599 reports
- Dizziness: 554 reports
Browse all side effects of Simcor:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Carvedilol side effects:
- Fatigue (feeling of tiredness): 6,610 reports
- Breathing difficulty: 6,175 reports
- Hypotension (abnormally low blood pressure): 5,548 reports
- Diarrhea: 4,974 reports
- Dizziness: 4,960 reports
- Weakness: 4,730 reports
Browse all side effects of Carvedilol:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study is based on niacin; simvastatin and carvedilol (the active ingredients of Simcor and Carvedilol, respectively). Other drugs that have the same active ingredients (e.g. generic drugs or brand names) are also considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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