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Fistula and drugs of ingredients of buprenorphine hydrochloride; naloxone hydrochloride (a real world drug study)


Summary:

Fistula is found among people who take drugs with ingredients of buprenorphine hydrochloride; naloxone hydrochloride, especially for people who are male, 40-49 old . This phase IV clinical study is created by eHealthMe based on reports of 35,338 people who have side effects when taking drugs with ingredients of buprenorphine hydrochloride; naloxone hydrochloride from the FDA, and is updated regularly.

Drug(s) considered in the study (i.e. both brand name and generic drugs): Bunavail, Buprenorphine hydrochloride and naloxone hydrochloride, Buprenorphine hydrochloride; naloxone hydrochloride, Cassipa, Suboxone, Zubsolv.

On Aug, 01, 2026

35,338 people reported to have side effects when taking drugs with ingredients of buprenorphine hydrochloride; naloxone hydrochloride.
Among them, 11 people (0.03%) have Fistula

What is Fistula?

Fistula (an abnormal connection or passageway between two) is found to be associated with 842 drugs and 906 conditions by eHealthMe. Check the latest studies of Fistula.

Number of reports submitted per year:

Could drugs with ingredients of buprenorphine hydrochloride; naloxone hydrochloride cause Fistula?

Gender of people who have Fistula when taking drugs with ingredients of buprenorphine hydrochloride; naloxone hydrochloride *:

  • female: 0.0 %
  • male: 100 %

Age of people who have Fistula when taking drugs with ingredients of buprenorphine hydrochloride; naloxone hydrochloride *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 100 %
  • 50-59: 0.0 %
  • 60+: 0.0 %

Conditions people have *:

You may use this to check any potential undetected conditions.

  1. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 6 people, 54.55%
  2. Drug Dependence: 4 people, 36.36%
  3. Pain: 3 people, 27.27%
  4. Drug Withdrawal Syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation): 2 people, 18.18%
  5. Withdrawal Syndrome (a discontinuation syndrome is a set of symptoms occurred due to discontinuation of substance): 1 person, 9.09%
  6. Sleep Disorder: 1 person, 9.09%
  7. Joint Pain: 1 person, 9.09%
  8. Gastrointestinal Stromal Tumor: 1 person, 9.09%
  9. Foetal Exposure During Pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect): 1 person, 9.09%

Other drugs people take *:

You may use this to check any potential interacting drugs.

  1. Olanzapine: 5 people, 45.45%
  2. Inflectra: 4 people, 36.36%
  3. Valium: 4 people, 36.36%
  4. Subutex: 4 people, 36.36%
  5. Vicodin: 1 person, 9.09%
  6. Azathioprine: 1 person, 9.09%
  7. Coumadin: 1 person, 9.09%
  8. Diazepam: 1 person, 9.09%
  9. Gleevec: 1 person, 9.09%
  10. Humira: 1 person, 9.09%

Other side effects people have besides Fistula *:

You may use this to check any potential undetected side effects.

  1. Joint Pain: 8 people, 72.73%
  2. Oropharyngeal Pain: 5 people, 45.45%
  3. Fatigue (feeling of tiredness): 5 people, 45.45%
  4. Malaise (a feeling of general discomfort or uneasiness): 5 people, 45.45%
  5. Pneumonia: 5 people, 45.45%
  6. Impaired Driving Ability: 4 people, 36.36%
  7. Weight Decreased: 3 people, 27.27%
  8. Death: 3 people, 27.27%
  9. Dyspnea (difficult or laboured breathing): 3 people, 27.27%
  10. Gastrointestinal Haemorrhage (bleeding gastrointestinal tract): 3 people, 27.27%

* Approximation only. Some reports may have incomplete information.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Related studies

Drugs with ingredients of buprenorphine hydrochloride; naloxone hydrochloride, their effectiveness, alternatives and more:

How the study uses the data?

The study uses data from the FDA. It is based on buprenorphine hydrochloride; naloxone hydrochloride. All drugs that have the same active ingredients (e.g. brand name and generic drugs) are considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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