Multiple-drug resistance and drugs of ingredients of methotrexate sodium (a real world drug study)
Summary:
Multiple-drug resistance is found among people who take drugs with ingredients of methotrexate sodium, especially for people who are female, 40-49 old , have been taking the drugs for 1 - 2 years. This phase IV clinical study is created by eHealthMe based on reports of 601,142 people who have side effects when taking drugs with ingredients of methotrexate sodium from the FDA, and is updated regularly.
Drug(s) considered in the study (i.e. both brand name and generic drugs): Abitrexate, Folex, Folex pfs, Methoblastin, Methotrexate, Methotrexate lpf, Methotrexate preservative free, Methotrexate sodium, Methotrexate sodium preservative free, Mexate, Mexate-aq, Mexate-aq preserved, Trexall, Xatmep.
601,142 people reported to have side effects when taking drugs with ingredients of methotrexate sodium.
Among them, 186 people (0.03%) have Multiple-drug resistance
What is Multiple-drug resistance?
Multiple-drug resistance is found to be associated with 245 drugs and 254 conditions by eHealthMe. Check the latest studies of Multiple-drug resistance.
Number of reports submitted per year:

Time on drugs with ingredients of methotrexate sodium when people have Multiple-drug resistance *:
- < 1 month: 35.29 %
- 1 - 6 months: 17.65 %
- 6 - 12 months: 5.88 %
- 1 - 2 years: 41.18 %
- 2 - 5 years: 0.0 %
- 5 - 10 years: 0.0 %
- 10+ years: 0.0 %
Gender of people who have Multiple-drug resistance when taking drugs with ingredients of methotrexate sodium *:
- female: 51.43 %
- male: 48.57 %
Age of people who have Multiple-drug resistance when taking drugs with ingredients of methotrexate sodium *:
- 0-1: 0.87 %
- 2-9: 4.35 %
- 10-19: 6.96 %
- 20-29: 18.26 %
- 30-39: 7.83 %
- 40-49: 24.35 %
- 50-59: 19.13 %
- 60+: 18.26 %
Conditions people have *:
You may use this to check any potential undetected conditions.
Other drugs people take *:
You may use this to check any potential interacting drugs.
Other side effects people have besides Multiple-drug resistance *:
You may use this to check any potential undetected side effects.
* Approximation only. Some reports may have incomplete information.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Related publications that referenced our studies
- Henien M, Carey B, Hullah E, Sproat C, Patel V, "methotrexate-associated osteonecrosis of the jaw: A report of two cases", Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, 2017 Dec .
- Henien M, Carey B, Hullah E, Sproat C, Patel V, "methotrexate-associated osteonecrosis of the jaw: A report of two cases", Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, 2017 Dec .
Related studies
Drugs with ingredients of methotrexate sodium, their effectiveness, alternatives and more:
How the study uses the data?
The study uses data from the FDA. It is based on methotrexate sodium. All drugs that have the same active ingredients (e.g. brand name and generic drugs) are considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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