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Fever and drugs of ingredients of methylphenidate (a real world drug study)


Summary:

Fever is found among people who take drugs with ingredients of methylphenidate, especially for people who are male, 40-49 old , have been taking the drugs for 1 - 6 months. This phase IV clinical study is created by eHealthMe based on reports of 24,433 people who have side effects when taking drugs with ingredients of methylphenidate from the FDA, and is updated regularly.

Drug(s) considered in the study (i.e. both brand name and generic drugs): Cotempla xr-odt, Daytrana, Methylphenidate.

On Jan, 11, 2026

24,433 people reported to have side effects when taking drugs with ingredients of methylphenidate.
Among them, 184 people (0.75%) have Fever

What is Fever?

Fever is found to be associated with 3,492 drugs and 6,152 conditions by eHealthMe. Check the latest studies of Fever.

Number of reports submitted per year:

Could drugs with ingredients of methylphenidate cause Fever?

Time on drugs with ingredients of methylphenidate when people have Fever *:

  • < 1 month: 25.0 %
  • 1 - 6 months: 31.25 %
  • 6 - 12 months: 6.25 %
  • 1 - 2 years: 25.0 %
  • 2 - 5 years: 12.5 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Fever when taking drugs with ingredients of methylphenidate *:

  • female: 43.56 %
  • male: 56.44 %

Age of people who have Fever when taking drugs with ingredients of methylphenidate *:

  • 0-1: 0.0 %
  • 2-9: 16.9 %
  • 10-19: 11.97 %
  • 20-29: 8.45 %
  • 30-39: 12.68 %
  • 40-49: 22.54 %
  • 50-59: 17.61 %
  • 60+: 9.86 %

Conditions people have *:

You may use this to check any potential undetected conditions.

  1. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 19 people, 10.33%
  2. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 15 people, 8.15%
  3. Pain: 12 people, 6.52%
  4. Drowsiness: 9 people, 4.89%
  5. Anaesthesia: 6 people, 3.26%
  6. Stress And Anxiety: 6 people, 3.26%
  7. General Anaesthesia: 6 people, 3.26%
  8. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 6 people, 3.26%
  9. Fatigue (feeling of tiredness): 6 people, 3.26%
  10. Primary Immunodeficiency Syndrome: 6 people, 3.26%

Other drugs people take *:

You may use this to check any potential interacting drugs.

  1. Ondansetron: 30 people, 16.30%
  2. Prednisone: 22 people, 11.96%
  3. Vitamin D3: 21 people, 11.41%
  4. Pantoprazole: 17 people, 9.24%
  5. Calcium: 14 people, 7.61%
  6. Wellbutrin: 13 people, 7.07%
  7. Zopiclone: 11 people, 5.98%
  8. Escitalopram: 10 people, 5.43%
  9. Inflectra: 9 people, 4.89%
  10. Hydroxyzine: 9 people, 4.89%

Other side effects people have besides Fever *:

You may use this to check any potential undetected side effects.

  1. Fatigue (feeling of tiredness): 46 people, 25.00%
  2. Nausea (feeling of having an urge to vomit): 44 people, 23.91%
  3. Headache (pain in head): 43 people, 23.37%
  4. Malaise (a feeling of general discomfort or uneasiness): 37 people, 20.11%
  5. High Blood Pressure: 35 people, 19.02%
  6. Dyspnea (difficult or laboured breathing): 30 people, 16.30%
  7. Nausea And Vomiting: 27 people, 14.67%
  8. Diarrhea: 26 people, 14.13%
  9. Pain: 24 people, 13.04%
  10. Feeling Abnormal: 21 people, 11.41%

* Approximation only. Some reports may have incomplete information.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Related publications that referenced our studies

Related studies

Drugs with ingredients of methylphenidate, their effectiveness, alternatives and more:

How the study uses the data?

The study uses data from the FDA. It is based on methylphenidate. All drugs that have the same active ingredients (e.g. brand name and generic drugs) are considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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