Cell death and drugs of ingredients of prednisolone (a real world drug study)
Summary:
Cell death is found among people who take drugs with ingredients of prednisolone, especially for people who are male, 60+ old , have been taking the drugs for 2 - 5 years. This phase IV clinical study is created by eHealthMe based on reports of 212,631 people who have side effects when taking drugs with ingredients of prednisolone from the FDA, and is updated regularly.
Drug(s) considered in the study (i.e. both brand name and generic drugs): Cortalone, Delta-cortef, Fernisolone-p, Meti-derm, Prednisolone, Prelone, Sterane.
212,631 people reported to have side effects when taking drugs with ingredients of prednisolone.
Among them, 47 people (0.02%) died.
Number of reports submitted per year:

Time on drugs with ingredients of prednisolone when people died *:
- < 1 month: 0.0 %
- 1 - 6 months: 0.0 %
- 6 - 12 months: 0.0 %
- 1 - 2 years: 0.0 %
- 2 - 5 years: 100 %
- 5 - 10 years: 0.0 %
- 10+ years: 0.0 %
Gender of people who died when taking drugs with ingredients of prednisolone *:
- female: 45.24 %
- male: 54.76 %
Age of people who died when taking drugs with ingredients of prednisolone *:
- 0-1: 2.38 %
- 2-9: 4.76 %
- 10-19: 0.0 %
- 20-29: 0.0 %
- 30-39: 2.38 %
- 40-49: 7.14 %
- 50-59: 21.43 %
- 60+: 61.9 %
Conditions people have *:
You may use this to check any potential undetected conditions.
- Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 12 people, 25.53%
- Psoriasis (immune-mediated disease that affects the skin): 12 people, 25.53%
- High Blood Cholesterol: 8 people, 17.02%
- Arthritis (form of joint disorder that involves inflammation of one or more joints): 7 people, 14.89%
- Thyroid Diseases: 7 people, 14.89%
- Joint Pain: 7 people, 14.89%
- High Blood Pressure: 4 people, 8.51%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 6.38%
- Glioblastoma (most common and most aggressive malignant primary brain tumour in humans): 3 people, 6.38%
- Insomnia (sleeplessness): 3 people, 6.38%
Other drugs people take *:
You may use this to check any potential interacting drugs.
- Paracetamol: 9 people, 19.15%
- Lipitor: 8 people, 17.02%
- Atrovent: 8 people, 17.02%
- Methotrexate: 8 people, 17.02%
- Clopidogrel: 8 people, 17.02%
- Taltz: 7 people, 14.89%
- Augmentin: 7 people, 14.89%
- Humira: 7 people, 14.89%
- Amlodipine: 5 people, 10.64%
- Plaquenil: 5 people, 10.64%
Other side effects people have when they died *:
- Cholestasis (a condition where bile cannot flow from the liver to the duodenum): 25 people, 53.19%
- Fever: 21 people, 44.68%
- Rashes (redness): 19 people, 40.43%
- Joint Pain: 18 people, 38.30%
- Psoriasis (immune-mediated disease that affects the skin): 15 people, 31.91%
- Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 10 people, 21.28%
- Swallowing Pain Or Burning: 10 people, 21.28%
- Jaundice - Yellow Skin (a yellowish pigmentation of the skin): 10 people, 21.28%
- Canker Sores (painful, open sore in the mouth): 10 people, 21.28%
- Skin Ulcer: 10 people, 21.28%
* Approximation only. Some reports may have incomplete information.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Related publications that referenced our studies
- Abdullah, D., Mohamed, A. M. F. S., & Liew, A. K. C., "Dentine hypersensitivity-like tooth pain associated with the use of high-dose steroid therapy", Journal of conservative dentistry: JCD, 2018 Jan .
- Abdullah, D., Mohamed, A. M. F. S., & Liew, A. K. C., "Dentine hypersensitivity-like tooth pain associated with the use of high-dose steroid therapy", Journal of conservative dentistry: JCD, 2018 Jan .
Related studies
Drugs with ingredients of prednisolone, their effectiveness, alternatives and more:
How the study uses the data?
The study uses data from the FDA. It is based on prednisolone. All drugs that have the same active ingredients (e.g. brand name and generic drugs) are considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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