Personalized prediction for a 63 year old woman who takes Lisinopril And Hydrochlorothiazide, Omeprazole Magnesium, Wellbutrin Xl (an AI-powered real world drug study)
Summary:
This is a personalized prediction of potential side effects and undetected conditions for up to one year, if you would have adverse effects. The study is created by eHealthMe based on data from the FDA.
On Sep, 09, 2025, 5,595,057 related reports were analyzed:

What are the drugs?
- Lisinopril and hydrochlorothiazide has active ingredients of hydrochlorothiazide; lisinopril. It is often used in high blood pressure. eHealthMe is studying from 10,247 Lisinopril and hydrochlorothiazide users. Check the latest studies of Lisinopril and hydrochlorothiazide.
- Omeprazole magnesium has active ingredients of omeprazole magnesium. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 6,953 Omeprazole magnesium users. Check the latest studies of Omeprazole magnesium.
- Wellbutrin xl has active ingredients of bupropion hydrochloride. It is often used in depression. eHealthMe is studying from 22,961 Wellbutrin xl users. Check the latest studies of Wellbutrin xl.
What are the conditions?
- Hypertension (high blood pressure) is found to be associated with 4,671 drugs and 5,180 conditions by eHealthMe. Check the latest studies of Hypertension.
- Reflux (stomach contents come back up into the food pipe (gullet or oesophagus) or even into the mouth) is found to be associated with 2,593 drugs and 3,431 conditions by eHealthMe. Check the latest studies of Reflux.
- Major depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings) is found to be associated with 870 drugs and 1,446 conditions by eHealthMe. Check the latest studies of Major depression.
Potential side effects:
- 5.47% for females aged 63 (±5) who have reflux and major depression
- 6.22% for females aged 63 (±5) who have reflux and major depression
- 11.16% for females aged 63 (±5) who have reflux and major depression
- 7.6% for females aged 63 (±5) who have major depression
- 5.77% for females aged 63 (±5) who have hypertension and major depression
- 5.3% for females aged 63 (±5) who have reflux and hypertension
- 6.18% for females aged 63 (±5) who have hypertension and major depression
- 5.16% for females aged 63 (±5) who have reflux and hypertension
- 6.56% for females aged 63 (±5) who have hypertension and major depression
- 6.06% for females aged 63 (±5) who have reflux and hypertension
- 5.74% for females aged 63 (±5) who take lisinopril and hydrochlorothiazide
- 5.74% for females aged 63 (±5) who have reflux and major depression
- 5.74% for females aged 63 (±5) who take omeprazole magnesium
- 5.74% for females aged 63 (±5) who take wellbutrin xl
- 5.63% for females aged 63 (±5) who have hypertension and major depression
- 5.05% for females aged 63 (±5) who have reflux and hypertension
- 6.31% for females aged 63 (±5) who have hypertension and major depression
- 5.78% for females aged 63 (±5) who take lisinopril and hydrochlorothiazide
- 5.78% for females aged 63 (±5) who take omeprazole magnesium
- 5.78% for females aged 63 (±5) who take wellbutrin xl
- 5.47% for females aged 63 (±5) who have reflux and hypertension
- 6.0% for females aged 63 (±5) who have hypertension and major depression
- 5.23% for females aged 63 (±5) who have reflux and hypertension
- 8.28% for females aged 63 (±5) who have hypertension and major depression
- 6.56% for females aged 63 (±5) who have reflux and hypertension
- 5.47% for females aged 63 (±5) who have major depression
- 7.08% for females aged 63 (±5) who have hypertension and major depression
- 6.39% for females aged 63 (±5) who have reflux and hypertension
- 6.1% for females aged 63 (±5) who take lisinopril and hydrochlorothiazide
- 6.1% for females aged 63 (±5) who take omeprazole magnesium
- 6.1% for females aged 63 (±5) who take wellbutrin xl
- 5.15% for females aged 63 (±5) who have reflux and major depression
- 5.05% for females aged 63 (±5) who have hypertension
- 6.74% for females aged 63 (±5) who have major depression
- 5.07% for females aged 63 (±5) who have hypertension and major depression
Potential co-existing conditions:
- 6.22% for females aged 63 (±5) who have reflux and major depression
- 5.37% for females aged 63 (±5) who have reflux and major depression
- 12.06% for females aged 63 (±5) who have hypertension and major depression
- 9.94% for females aged 63 (±5) who have reflux and hypertension
- 6.54% for females aged 63 (±5) who have reflux and major depression
- 17.54% for females aged 63 (±5) who have hypertension and major depression
- 15.89% for females aged 63 (±5) who have reflux and hypertension
- 15.12% for females aged 63 (±5) who have reflux and major depression
- 7.92% for females aged 63 (±5) who have hypertension and major depression
- 7.0% for females aged 63 (±5) who have reflux and hypertension
- 6.19% for females aged 63 (±5) who have reflux and major depression
- 13.24% for females aged 63 (±5) who have reflux and major depression
- 10.81% for females aged 63 (±5) who have hypertension and major depression
- 10.68% for females aged 63 (±5) who have reflux and hypertension
- 11.08% for females aged 63 (±5) who take lisinopril and hydrochlorothiazide
- 11.08% for females aged 63 (±5) who take omeprazole magnesium
- 11.08% for females aged 63 (±5) who take wellbutrin xl
- 10.39% for females aged 63 (±5) who have hypertension and major depression
- 9.05% for females aged 63 (±5) who have reflux and hypertension
- 6.35% for females aged 63 (±5) who have reflux and major depression
- 6.32% for females aged 63 (±5) who have hypertension and major depression
- 5.08% for females aged 63 (±5) who have reflux and hypertension
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
How the study uses the data?
The study is based on gender, age, active ingredients of any drugs used, and more. Other drugs that have the same active ingredients (e.g. generic drugs) are considered.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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