Abilify and Tylenol w/ codeine no. 3 drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Abilify (aripiprazole) and Tylenol w/ codeine no. 3 (acetaminophen; codeine phosphate). Common drug interactions include neuropathy peripheral among females and anxiety among males.

The phase IV clinical study analyzes what interactions people have when they take Abilify and Tylenol w/ codeine no. 3. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.

What is Abilify?

Abilify has active ingredients of aripiprazole. It is often used in depression. eHealthMe is studying from 101,454 Abilify users. Check the latest studies of Abilify.

What is Tylenol w/ codeine no. 3?

Tylenol w/ codeine no. 3 has active ingredients of acetaminophen; codeine phosphate. It is often used in pain. eHealthMe is studying from 4,920 Tylenol w/ codeine no. 3 users. Check the latest studies of Tylenol w/ codeine no. 3.



On Jul, 14, 2026

16 people who take Abilify and Tylenol w/ codeine no. 3 together, and have interactions are studied.

Abilify and Tylenol w/ codeine no. 3 drug interactions.

What are the common drug interactions of Abilify and Tylenol W/ Codeine No. 3, by gender? *:

female:

  1. Neuropathy peripheral (surface nerve damage)
  2. Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)
  3. Headache (pain in head)
  4. Psychotic disorder
  5. Diabetes mellitus inadequate control
  6. Type 2 diabetes mellitus
  7. Amenorrhoea (absence of a menstrual period in a woman of reproductive age)
  8. Anaemia (lack of blood)
  9. Bladder prolapse (bulging of one or more of the pelvic organs into the vagina)
  10. Bone pain

male:

  1. Anxiety
  2. Emotional distress
  3. Nightmare (unpleasant dream)
  4. Pneumonia
  5. Fear
  6. Foetal exposure during pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect)
  7. Injury
  8. Premature baby
  9. Renal failure (kidney dysfunction)
  10. Renal impairment (severely reduced kidney function)

What are the common drug interactions of Abilify and Tylenol W/ Codeine No. 3, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  2. Dry mouth
  3. Pharyngeal oedema (abnormal accumulation of fluid in the cavities and intercellular spaces of the pharyngeal)
  4. Pulmonary embolism (blockage of the main artery of the lung)

30-39:

  1. Amenorrhoea (absence of a menstrual period in a woman of reproductive age)
  2. Anaemia (lack of blood)
  3. Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)
  4. Central obesity (belly fat)
  5. Chest pain
  6. Contusion (a type of hematoma of tissue in which capillaries)
  7. Diabetes mellitus non-insulin-dependent
  8. Dyspnoea (difficult or laboured respiration)
  9. Fatigue (feeling of tiredness)
  10. General physical condition

40-49:

  1. Diabetes mellitus inadequate control
  2. Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)
  3. Metabolic syndrome (a combination of the medical disorders that, when occurring together, increase the risk of developing cardiovascular disease)
  4. Neuropathy peripheral (surface nerve damage)
  5. Type 2 diabetes mellitus
  6. Diarrhoea
  7. Nightmare (unpleasant dream)
  8. Pneumonia
  9. Psychotic disorder

50-59:

  1. Asthenia (weakness)
  2. Blood glucose increased
  3. Decreased appetite
  4. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  5. Diabetes mellitus inadequate control
  6. Hallucination, auditory (perceiving sounds without auditory stimulus)
  7. Homicidal ideation (thoughts about human killing another human)
  8. Hyperglycaemia (high blood sugar)
  9. Major depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings)
  10. Mood swings (an extreme or rapid change in mood)

60+:

  1. Anxiety
  2. Emotional distress
  3. Bladder prolapse (bulging of one or more of the pelvic organs into the vagina)
  4. Bone pain
  5. Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)
  6. Colonic polyp (extra part of colon tissue grow in intestine)
  7. Diabetic foot
  8. Diabetic retinopathy (damage to the retina caused by complications of diabetes)
  9. Diverticulum intestinal (a pouch that is attached to the first part of the small intestine)
  10. Foot fracture

What are the existing conditions these people have? *

  1. Stress And Anxiety: 4 people, 25.00%
  2. Bipolar Disorder (mood disorder): 4 people, 25.00%
  3. High Blood Pressure: 3 people, 18.75%
  4. Insomnia (sleeplessness): 3 people, 18.75%
  5. Post-Traumatic Stress Disorder: 2 people, 12.50%
  6. Diabetes: 2 people, 12.50%
  7. Dizziness: 2 people, 12.50%
  8. Migraine (headache): 2 people, 12.50%
  9. Thyroid Diseases: 2 people, 12.50%
  10. Laxative Supportive Care: 2 people, 12.50%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Abilify and Tylenol w/ codeine no. 3:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Abilify:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Tylenol w/ codeine no. 3:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Abilify and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Tylenol w/ codeine no. 3 and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on aripiprazole and acetaminophen; codeine phosphate (the active ingredients of Abilify and Tylenol w/ codeine no. 3, respectively), and Abilify and Tylenol w/ codeine no. 3 (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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