Accolate and Diovan drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Accolate (zafirlukast) and Diovan (valsartan). Common drug interactions include dental caries among females and diarrhoea among males.
The phase IV clinical study analyzes what interactions people have when they take Accolate and Diovan. It is created by eHealthMe based on reports of 97 people who take the same drugs from the FDA, and is updated regularly.
What is Accolate?
Accolate has active ingredients of zafirlukast. It is often used in asthma. eHealthMe is studying from 4,220 Accolate users. Check the latest studies of Accolate.
What is Diovan?
Diovan has active ingredients of valsartan. It is often used in high blood pressure. eHealthMe is studying from 83,153 Diovan users. Check the latest studies of Diovan.
97 people who take Accolate and Diovan together, and have interactions are studied.

What are the common drug interactions of Accolate and Diovan, by gender? *:
female:
- Dental caries
- Dizziness
- Dysphagia (a condition in which swallowing is difficult or painful)
- Headache (pain in head)
- Hepatic steatosis (fatty liver disease)
- Hiatus hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)
- Impaired healing
- Pain in jaw
- Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
male:
- Diarrhoea
- Headache (pain in head)
- Blood bilirubin increased
- Cardiomegaly (increased size of heart than normal)
- Chronic kidney disease
- Cough
- Depression
- Diabetes mellitus inadequate control
- Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)
- Dyspnoea (difficult or laboured respiration)
What are the common drug interactions of Accolate and Diovan, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Meningitis aseptic (a condition that causes the membranes covering your brain and spinal cord to become inflamed)
- Influenza like illness
- Injection site reaction
- Nausea (feeling of having an urge to vomit)
- Neck pain
- Vomiting
- Abdominal pain
- Alveolitis allergic (inflammation of the alveoli within the lung caused by hypersensitivity to inhaled organic dusts)
- Discomfort
- Flatulence (flatus expelled through the anus)
40-49:
- Blood pressure decreased
- Dyspnoea (difficult or laboured respiration)
- Erythema (redness of the skin)
- Eschar (dead tissue that falls off (sheds) from healthy skin)
- Fatigue (feeling of tiredness)
- Generalised oedema (swelling all over the body)
- Musculoskeletal chest pain (pain in chest muscle or nerve or bones)
- Pollakiuria (abnormally frequent passage of relatively small quantities or urine)
- Pruritus (severe itching of the skin)
- Skin discolouration (change of skin colour)
50-59:
- Palpitations (feelings or sensations that your heart is pounding or racing)
- Anxiety
- Arthralgia (joint pain)
- Diabetes mellitus inadequate control
- Fall
- Hyperlipidaemia (presence of excess lipids in the blood)
- Vomiting
- Dental caries
- Hypersensitivity
- Pain in jaw
60+:
- Haemoglobin decreased
- Hemiplegia (paralysis of one side of the body)
- Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
- Pneumonia
- Rash
- Red blood cell sedimentation rate increased
- Splenomegaly (enlargement of spleen)
- Swelling face
- Tenderness (pain or discomfort when an affected area is touched)
- White blood cell count increased
What are the existing conditions these people have? *
- Osteoporosis (bones weak and more likely to break): 14 people, 14.43%
- Pain: 9 people, 9.28%
- Type 2 Diabetes: 6 people, 6.19%
- Migraine (headache): 6 people, 6.19%
- Arthritis (form of joint disorder that involves inflammation of one or more joints): 6 people, 6.19%
- Immunodeficiency Common Variable: 5 people, 5.15%
* Approximation only. Some reports may have incomplete information.
Do you take Accolate and Diovan?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Accolate and Diovan:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Accolate:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Diovan:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Accolate and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Diovan and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on zafirlukast and valsartan (the active ingredients of Accolate and Diovan, respectively), and Accolate and Diovan (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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