Accutane and Pradaxa drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Accutane (isotretinoin) and Pradaxa (dabigatran etexilate mesylate). Common drug interactions include asthenia among females and inflammatory bowel disease among males.

The phase IV clinical study analyzes what interactions people have when they take Accutane and Pradaxa. It is created by eHealthMe based on reports of 20 people who take the same drugs from the FDA, and is updated regularly.

What is Accutane?

Accutane has active ingredients of isotretinoin. It is often used in acne. eHealthMe is studying from 35,221 Accutane users. Check the latest studies of Accutane.

What is Pradaxa?

Pradaxa has active ingredients of dabigatran etexilate mesylate. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 86,906 Pradaxa users. Check the latest studies of Pradaxa.

On Jul, 26, 2026

20 people who take Accutane and Pradaxa together, and have interactions are studied.

What are the common drug interactions of Accutane and Pradaxa, by gender? *:

female:

Asthenia (weakness)
Asthma
Attention deficit/hyperactivity disorder
Blood fibrinogen decreased
Blood pressure increased
Cardiac arrest
Cardiac output decreased
Concussion (short loss of normal brain function in response to a head injury)
Cough
Dementia (madness)

male:

Inflammatory bowel disease
Colitis ulcerative (inflammation of colon with ulcer)
Anal fistula
Stress
Blood alkaline phosphatase increased
Blood cholesterol increased
Intestinal haemorrhage (bleeding from intestine)
Proctitis ulcerative (inflammation of the rectum and anus ulcerative)
Pyoderma gangrenosum (ulcerating condition of skin that results in heaped borders with a typical appearance)
Anaemia (lack of blood)

What are the common drug interactions of Accutane and Pradaxa, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

Inflammatory bowel disease
Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)
Intestinal haemorrhage (bleeding from intestine)
Anaemia (lack of blood)
Anal fistula
Cough
Nausea (feeling of having an urge to vomit)
Blood cholesterol increased
Proctitis ulcerative (inflammation of the rectum and anus ulcerative)
Anal abscess

What are the existing conditions these people have? *

High Blood Pressure: 7 people, 35.00%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 20.00%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 10.00%
High Blood Cholesterol: 2 people, 10.00%
Fluid Retention (an abnormal accumulation of fluid in the blood): 2 people, 10.00%
Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 1 person, 5.00%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 1 person, 5.00%
Atherosclerosis (disorder of the arteries): 1 person, 5.00%
Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 1 person, 5.00%
Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it): 1 person, 5.00%

* Approximation only. Some reports may have incomplete information.

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